CAS 3556-56-7

N-[(Phenylmethoxy)carbonyl]-L-tyrosine 4-nitrophenyl ester

Description:

N-[(Phenylmethoxy)carbonyl]-L-tyrosine 4-nitrophenyl ester, with CAS number 3556-56-7, is a chemical compound that belongs to the class of amino acid derivatives. It features a tyrosine backbone, which is an aromatic amino acid known for its role in protein synthesis and as a precursor for neurotransmitters. The compound is characterized by the presence of a phenylmethoxycarbonyl (Pmc) protecting group, which is commonly used in peptide synthesis to protect the amino group of the amino acid. Additionally, the 4-nitrophenyl ester moiety contributes to its reactivity, making it useful in various chemical reactions, particularly in the synthesis of peptides and other complex organic molecules. The compound is typically a solid at room temperature and may exhibit solubility in organic solvents. Its properties, such as melting point, solubility, and reactivity, can vary based on the specific conditions and purity of the sample. Overall, this compound is significant in organic synthesis and biochemistry, particularly in the development of pharmaceuticals and bioconjugates.

Formula: C₂₃H₂₀N₂O₇

InChI: InChI=1S/C23H20N2O7/c26-19-10-6-16(7-11-19)14-21(24-23(28)31-15-17-4-2-1-3-5-17)22(27)32-20-12-8-18(9-13-20)25(29)30/h1-13,21,26H,14-15H2,(H,24,28)/t21-/m0/s1

InChI key: InChIKey=WUHIFOXZYIQZFP-NRFANRHFSA-N

SMILES: [C@H](CC1=CC=C(O)C=C1)(C(OC2=CC=C(N(=O)=O)C=C2)=O)NC(OCC3=CC=CC=C3)=O

Synonyms:

• 4-nitrophenyl N-[(benzyloxy)carbonyl]tyrosinate
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-CBZ-L-Tyrosine-p-nitrophenyl ester N-Carbobenzyloxy-L-tyrosine-p-nitrophenyl ester
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine 4-nitrophenyl ester
• N-α-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• NSC 88489
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, <span class="text-smallcaps">L</span>-
• Z-Tyr-ONp
• p-Nitrophenyl N-benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• α-N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, L-
• N-α-Carbobenzoxy-L-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-L-tyrosine 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-L-tyrosine p-nitrophenyl ester

Z-Tyr-Onp

CAS: 3556-56-7

Formula: C₂₃H₂₀N₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 436.4141

Ref: IN-DA00BYAK

Z-Tyr-Onp

CAS: 3556-56-7

Z-Tyr-Onp

Purity: 98%

Molecular weight: 436.41g/mol

Ref: 54-OR1015469

Z-L-tyrosine 4-nitrophenyl ester

CAS: 3556-56-7

Z-L-tyrosine 4-nitrophenyl ester is a synthetic, inactivated amide that binds to the active site of enzyme, preventing its enzymatic activity. It prevents the formation of clots by cleaving the clotting factors and is used in blood transfusions. Z-L-tyrosine 4-nitrophenyl ester has been shown to inhibit the synthesis of surfactant and is used as an antiseptic. This drug can be prepared by reacting L-tyrosine with nitrophenol (NO2) in the presence of a base such as sodium hydroxide or potassium carbonate, followed by purification on sephadex g-100 columns. The product is then treated with hydrostatic pressure to remove any unreacted starting materials. This drug also has a sedimentation rate of about 1.5 x 10^6 cm/s.

Formula: C₂₃H₂₀N₂O₇

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 436.41 g/mol

Ref: 3D-FT47319

Z-Tyr-ONp

CAS: 3556-56-7

Z-Tyr-ONp is a synthetic, water soluble, non-toxic fibrinogen activator. It has been shown to be effective at low concentrations in the activation of fibrinogen and in the prevention of clotting. Z-Tyr-ONp hydrolyzes fibrinogen to form fibrin clots, which are needed for blood coagulation. This process is mediated by the enzyme alpha-thrombin and is dependent on calcium ions. Z-Tyr-ONp also exhibits surfactant properties that allow it to stabilize micelles that contain lipase enzymes and bile salts, which are required for digestion of dietary fats. The presence of lipase enzymes can enhance the proteolytic activity of Z-Tyr-ONp and increase its ability to dissolve clots.

Formula: C₂₃H₂₀N₂O₇

Purity: Min. 95%

Molecular weight: 436.41 g/mol

Ref: 3D-SYN-3016