CAS 3556-86-3

Methyl 3-hydroxy-4-methylbenzoate

Description:

Methyl 3-hydroxy-4-methylbenzoate, with the CAS number 3556-86-3, is an organic compound that belongs to the class of benzoates. It features a methyl ester functional group, which is derived from benzoic acid, and contains both hydroxyl and methyl substituents on the aromatic ring. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is characterized by its pleasant, floral aroma, making it useful in the fragrance and flavoring industries. The presence of the hydroxyl group contributes to its solubility in polar solvents, while the methyl ester enhances its volatility. Methyl 3-hydroxy-4-methylbenzoate may also exhibit biological activity, which can be of interest in pharmaceutical applications. As with many organic compounds, it should be handled with care, observing appropriate safety protocols to mitigate any potential hazards associated with its use.

Formula: C₈H₇O₃

InChI: InChI=1/C8H8O3/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,9H,1H3,(H,10,11)/p-1

InChI key: GCSINTLJUNXLLU-UHFFFAOYSA-N

SMILES: Cc1ccc(cc1[O-])C(=O)O

Synonyms:

• 3-Hydroxy-4-Methylbenzoate

Methyl 3-hydroxy-4-methylbenzoate

CAS: 3556-86-3

Formula: C₉H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.1739

Ref: IN-DA00I723

Methyl 4-Methyl-3-hydroxybenzoate

Controlled Product

CAS: 3556-86-3

Applications Methyl 4-Methyl-3-hydroxybenzoate is used in the preparation of potent antimalarial agents. Also used in the preparation of aromatic inhibtors of anthranilate synthase.
References Fattorusso, C. et al.: J. Med. Chem., 51, 1333 (2008); Payne, R. et al.: Org. biomol. Chem., 3, 3629 (2005);

Formula: C₉H₁₀O₃

Color and Shape: Neat

Molecular weight: 166.17

Ref: TR-M322970

Methyl 3-hydroxy-4-methylbenzoate

CAS: 3556-86-3

Methyl 3-hydroxy-4-methylbenzoate

Formula: C₉H₁₀O₃

Purity: ≥95%

Molecular weight: 166.1739

Ref: 54-OR311176

Methyl 3-hydroxy-4-methylbenzoate

CAS: 3556-86-3

Methyl 3-hydroxy-4-methylbenzoate

Formula: C₉H₁₀O₃

Purity: 98%

Molecular weight: 166.17

Ref: IN-DG20407

Methyl 3-hydroxy-4-methylbenzoate

CAS: 3556-86-3

Methyl 3-hydroxy-4-methylbenzoate (HMBA) is a metabolite of the anti-cancer drug methotrexate. HMBA has shown an inhibitory effect on acid phosphatase and on the growth of cancer cells. It also has an anti-inflammatory effect, which may be due to its ability to inhibit enzyme extracts from inflammatory diseases such as arthritis or asthma. HMBA has been shown to have a pharmacokinetic profile in vivo, which has been demonstrated by using SW620 cells. This compound is also able to cross the blood brain barrier and accumulate in cancerous tumors.

Formula: C₉H₁₀O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 166.17 g/mol

Ref: 3D-FM38416

Methyl 3-Hydroxy-4-methylbenzoate

CAS: 3556-86-3

Formula: C₉H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.176

Ref: 10-F066815