CAS 356068-93-4

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Description:

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, with CAS number 356068-93-4, is a synthetic organic compound characterized by its complex structure, which includes a pyrrole ring, a carboxylic acid functional group, and an indolinone moiety. The presence of the fluorine atom suggests potential for enhanced biological activity or altered physicochemical properties. This compound may exhibit interesting properties such as solubility in organic solvents, moderate stability under standard conditions, and potential reactivity due to the carboxylic acid group. Its unique structure may confer specific biological activities, making it a candidate for pharmaceutical research, particularly in the development of novel therapeutic agents. The compound's synthesis and characterization would typically involve techniques such as NMR spectroscopy, mass spectrometry, and possibly X-ray crystallography to confirm its molecular structure and purity. Overall, this compound represents a class of heterocyclic compounds that are of significant interest in medicinal chemistry and drug development.

Formula: C₁₆H₁₃FN₂O₃

InChI: InChI=1/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-

SMILES: Cc1c(/C=C\2/c3cc(ccc3N=C2O)F)[nH]c(C)c1C(=O)O

Synonyms:

• 1H-pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
• 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
• (Z)-5-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic Acid
• 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...
• (3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-on
• Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid
• (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic acid
• (3Z)-3-[(3,5-DiMethyl-4-carboxy-1H-pyrrol-2-yl)Methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one
• 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 300.28900146484375

Ref: 10-F238886

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Formula: C₁₆H₁₃FN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 300.2844

Ref: IN-DA0037KR

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Ref: 7W-GX6190

(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Purity: 98%

Molecular weight: 300.289g/mol

Ref: 54-PC99839

5-[(Z)-(5-Fluoro-2-oxo-indolin-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Controlled Product

CAS: 356068-93-4

Formula: C₁₆H₁₃FN₂O₃

Color and Shape: Neat

Molecular weight: 300.28

Ref: 86-MM3568.04

Sunitinib Impurity 13

CAS: 356068-93-4

Formula: C₁₆H₁₃FN₂O₃

Molecular weight: 300.3

Ref: ST-EA-CP-S42036

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl is an inhibitor of protein kinase. It inhibits the activity of protein kinase C (PKC) and also has immunosuppressive properties. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole is a white to off white crystalline powder that belongs to the class of pyrroles. It has been shown to be a vasotropic agent by binding to the alpha 1 beta 1 integrin receptor on vascular smooth muscle cells. This drug binds to aminophospholipids in plasma and can cause osteopathic lesions when injected into bone tissue. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole has been shown to have antiinflammatory effects

Formula: C₁₆H₁₃FN₂O₃

Purity: Min. 95%

Molecular weight: 300.28 g/mol

Ref: 3D-FF106180

Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid

Controlled Product

CAS: 356068-93-4

Applications Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid is an impurity of Sunitinib (S819995), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003); Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003); Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004); Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004)

Formula: C₁₆H₁₃FN₂O₃

Color and Shape: Neat

Molecular weight: 300.28

Ref: TR-D367070

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65586 and the CAS number is 356068-93-4.

Formula: C₁₆H₁₃FN₂O₃

Color and Shape: Solid

Molecular weight: 300.289

Ref: TM-T65586