CAS 35607-66-0

Cefoxitin

Description:

Cefoxitin is a semi-synthetic cephalosporin antibiotic that is primarily used to treat a variety of bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria, making it a broad-spectrum antibiotic. Cefoxitin works by inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. The compound is typically administered via injection and is often used in surgical prophylaxis, particularly in procedures involving the gastrointestinal tract, due to its effectiveness against anaerobic bacteria. Cefoxitin is characterized by its stability against certain beta-lactamases, enzymes produced by some bacteria that confer resistance to other antibiotics. Its chemical structure includes a beta-lactam ring, which is essential for its antibacterial activity. Common side effects may include gastrointestinal disturbances, allergic reactions, and potential interactions with other medications. As with all antibiotics, it is crucial to use Cefoxitin judiciously to prevent the development of antibiotic resistance.

Formula: C₁₆H₁₇N₃O₇S₂

InChI: InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14-,16+/m1/s1

InChI key: InChIKey=WZOZEZRFJCJXNZ-ZBFHGGJFSA-N

SMILES: N(C(CC1=CC=CS1)=O)[C@@]2(OC)[C@@]3(N(C2=O)C(C(O)=O)=C(COC(N)=O)CS3)[H]

Synonyms:

• (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7S)-3-[[(Aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R-cis)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-, (6R,7S)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-, (6R-cis)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, (6R,7S)-
• Cefoxitin Acid
• Cefoxitina
• Cefoxitine
• Cephoxitin

Cefoxitin

CAS: 35607-66-0

Formula: C₁₆H₁₇N₃O₇S₂

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 427.45

Ref: 3B-C3598

Cefoxitin, 98%

CAS: 35607-66-0

A broad spectrum antibiotic

Formula: C₁₆H₁₇N₃O₇S₂

Purity: 98%

Color and Shape: White to off-white, Powder

Molecular weight: 427.45

Ref: 02-J66891

Cefoxitin

CAS: 35607-66-0

Antibiotics nesoi

Formula: C₁₆H₁₇N₃O₇S₂

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 427.05079

Ref: 45-1098107

(6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 35607-66-0

Formula: C₁₆H₁₇N₃O₇S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 427.4521

Ref: IN-DA00I72E

Cefoxitin

CAS: 35607-66-0

Cefoxitin

Purity: 98%

Molecular weight: 427.45g/mol

Ref: 54-OR1029578

Cefoxitin

CAS: 35607-66-0

Cefoxitin, an oral 2nd-gen cephalosporin antibiotic, combats Gram+/- & anaerobes, for abdominal and gynecological infections.

Formula: C₁₆H₁₇N₃O₇S₂

Purity: 99.8% - 99.89%

Color and Shape: Solid

Molecular weight: 427.45

Ref: TM-T20643

Cefoxitin

CAS: 35607-66-0

Purity: 95%

Molecular weight: 427.450012207031

Ref: 10-F793555

Cefoxitin

Controlled Product

CAS: 35607-66-0

Applications Cefoxitin is a semi-synthetic antibiotic derived from Cephamycin C, possessing high resistance to β-lactamase inactivation. An antibacterial.
References Wallick, H., et al.: Antimicrob. Agents Chemother., 5, 25 (1974), Brenner, G.S., et al.: Anal. Profiles Drug Subs., 11, 169 (1982),

Formula: C₁₆H₁₇N₃O₇S₂

Color and Shape: Neat

Molecular weight: 427.45

Ref: TR-C243190

Cefoxitin

CAS: 35607-66-0

Inhibitor of cell-wall synthesis; cephalosporin class

Formula: C₁₆H₁₇N₃O₇S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 427.45 g/mol

Ref: 3D-FC144348

Cefoxitin S-Oxide

Controlled Product

CAS: 35607-66-0

Formula: C₁₆H₁₇N₃O₇S₂

Color and Shape: Neat

Molecular weight: 427.45

Ref: TR-C243210