CAS 3562-84-3
:benzbromarone
Description:
Benzbromarone is a synthetic organic compound primarily used as a uricosuric agent in the treatment of gout and hyperuricemia. It functions by inhibiting the reabsorption of uric acid in the kidneys, thereby promoting its excretion. The compound is characterized by its molecular formula, which includes a bromobenzene moiety, contributing to its pharmacological properties. Benzbromarone is typically administered orally and is known for its relatively high bioavailability. It exhibits a moderate to high solubility in organic solvents but is less soluble in water. The compound has a long half-life, allowing for once-daily dosing in clinical settings. Side effects may include gastrointestinal disturbances and, in rare cases, liver toxicity, necessitating monitoring of liver function during treatment. Benzbromarone's mechanism of action and efficacy make it a valuable option in managing conditions associated with elevated uric acid levels, although its use may be limited by potential adverse effects and contraindications in certain patient populations.
Formula:C17H12Br2O3
InChI:InChI=1/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
InChI key:InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N
SMILES:C(=O)(C=1C=2C(OC1CC)=CC=CC2)C3=CC(Br)=C(O)C(Br)=C3
Synonyms:- (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
- (3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone
- (3,5-Dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
- 2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran
- 3,5-Dibromo-4-Hydroxyphenyl-2-Ethylbenzo[B]Furan-3-Yl Ketone
- 3,5-Dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl ketone
- Azubromaron
- Benzbromaron
- Besuric
- Desuric
- Ketone, 3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl
- L 2214
- L 2214-Labaz
- Max-Uric
- Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-
- Minuric
- Mj 10061
- NSC 85433
- Narcaricin
- Normurat
- Uricovac
- Urinorm
- Benzbromarone
- mj10061
- BENZBROMARONE, MM(CRM STANDARD)
- l2214-labaz
- exurate
- l2214
- (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-methanon
- 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-benzofura
- (3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)ketone
- LABOTEST-BB LT00134669
- 3,5-dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranylketone
- 3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN
- ketone,3,5-dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranyl
- See more synonyms
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Found 19 products.
BENZBROMARONE CRS
CAS:BENZBROMARONE CRSFormula:C17H12Br2O3Color and Shape:Added ModifiedMolecular weight:424.0834Benzbromarone
CAS:<p>Benzbromarone (Desuric) is a CYP2C9 inhibitor with Ki value of 19.3 nM.</p>Formula:C17H12Br2O3Purity:99.37% - 99.73%Color and Shape:SolidMolecular weight:424.08Benzbromarone
CAS:Formula:C17H12Br2O3Purity:(GC) ≥ 98.0%Color and Shape:White to pale yellow powder or crystalsMolecular weight:424.08Benzbromarone
CAS:Formula:C17H12Br2O3Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:424.09Benzbromarone
CAS:Controlled Product<p>Applications Benzbromarone is a uricosuric agent used in the treatment of gout and hyperuricemia. Studies show that use of Benzbromarone results in less complications than other uricosuric agent such as Allopurinol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heel, R.C. et al.: Drugs, 14, 349 (1977); Perez-Ruiz, F. et al.: Ann. Rheum. Dis., 57, 545 (1998);<br></p>Formula:C17H12Br2O3Color and Shape:Off-WhiteMolecular weight:424.08Benzbromarone-D5
CAS:Controlled ProductFormula:C17D5H7Br2O3Color and Shape:NeatMolecular weight:429.114(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
CAS:<p>3,5-Dibromo-4-hydroxyphenyl-(2-ethyl-3-benzofuranyl)methanone (DBF) is a synthetic molecule that has been shown to be effective against obesity by reducing the size of fat cells. DBF was originally developed as an anti-inflammatory drug for psoriasis and arthritis. It has also been shown to have antioxidant and anti-cancer properties. DBF binds to toll-like receptor 4 (TLR4), which is involved in the inflammatory response, and inhibits its activation. This inhibition leads to a decrease in proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). DBF also reduces the mitochondrial membrane potential, which may be due to its ability to inhibit ATP production by mitochondria and/or block mitochondrial protein synthesis.</p>Formula:C17H12Br2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:424.08 g/mol
