CAS 35661-39-3: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine
Description:N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine, commonly referred to as Fmoc-L-alanine, is a derivative of the amino acid L-alanine, where the amino group is protected by a fluorenylmethoxycarbonyl (Fmoc) group. This compound is characterized by its stability under basic conditions, making it a popular choice in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The Fmoc group can be easily removed under mild basic conditions, allowing for the subsequent coupling of amino acids. Fmoc-L-alanine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its molecular structure includes a fluorenyl ring, which contributes to its unique properties, including fluorescence. The compound is widely used in biochemistry and medicinal chemistry for the synthesis of peptides and other bioactive molecules, facilitating the study of protein structure and function. Safety data should be consulted for handling and storage, as with all chemical substances.
Formula:C18H17NO4
InChI:InChI=1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1
InChI key:InChIKey=QWXZOFZKSQXPDC-NSHDSACASA-N
SMILES:O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC(C(=O)O)C
- Synonyms:
- (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]propanoic acid
- (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propanoic acid
- (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoate
- (9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-alanine
- (9-Fluorenylmethoxycarbonyl)-L-alanine
- (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propionic acid
- (S)-N-Fmoc-alanine
- <span class="text-smallcaps">L</span>-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- FMOC-<span class="text-smallcaps">L</span>-alanine
- FMOC-Ala-OH
- See more synonyms
- FMOC-Alanine
- Fmoc-L-Ala-OH Hydrate
- Fmoc-L-alanine
- L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- N-(9-Fluorenylmethoxycarbonyl)alanine
- N-9-Fluorenylmethoxycarbonyl-<span class="text-smallcaps">L</span>-alanine
- N-9-Fluorenylmethoxycarbonyl-L-alanine
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin
- N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-alanina
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]alanine
- N-[(9H-fluorene-9-ylmethoxy)carbonyl]-L-alanine
- Npc 14688
- Nsc 334296
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine
- Fmoc-L-Ala-OH