CAS 35661-39-3

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine, commonly referred to as Fmoc-L-alanine, is a derivative of the amino acid L-alanine, where the amino group is protected by a fluorenylmethoxycarbonyl (Fmoc) group. This compound is characterized by its stability under basic conditions, making it a popular choice in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The Fmoc group can be easily removed under mild basic conditions, allowing for the subsequent coupling of amino acids. Fmoc-L-alanine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its molecular structure includes a fluorenyl ring, which contributes to its unique properties, including fluorescence. The compound is widely used in biochemistry and medicinal chemistry for the synthesis of peptides and other bioactive molecules, facilitating the study of protein structure and function. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₁₈H₁₇NO₄

InChI: InChI=1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1

InChI key: InChIKey=QWXZOFZKSQXPDC-NSHDSACASA-N

SMILES: C(OC(N[C@H](C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]propanoic acid
• (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propanoic acid
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoate
• (9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-alanine
• (9-Fluorenylmethoxycarbonyl)-L-alanine
• (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propionic acid
• (S)-N-Fmoc-alanine
• <span class="text-smallcaps">L</span>-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-<span class="text-smallcaps">L</span>-alanine
• FMOC-Ala-OH
• FMOC-Alanine
• Fmoc-L-Ala-OH Hydrate
• Fmoc-L-alanine
• L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N-(9-Fluorenylmethoxycarbonyl)alanine
• N-9-Fluorenylmethoxycarbonyl-<span class="text-smallcaps">L</span>-alanine
• N-9-Fluorenylmethoxycarbonyl-L-alanine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin
• N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-alanina
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]alanine
• N-[(9H-fluorene-9-ylmethoxy)carbonyl]-L-alanine
• Npc 14688
• Nsc 334296
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine

CAS: 35661-39-3

Formula: C₁₈H₁₇NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 311.34

Ref: 3B-F0305

N-Fmoc-L-alanine, 95%

CAS: 35661-39-3

N-Fmoc-L-alanine is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility when incorporated into a polypeptide chain. The Fmoc g

Formula: C₁₈H₁₇NO₄

Purity: 95%

Molecular weight: 311.34

Ref: 02-H59438

Fmoc-Ala-OH

CAS: 35661-39-3

Formula: C₁₈H₁₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 311.3319

Ref: IN-DA00I72U

Fmoc-Ala-OH

CAS: 35661-39-3

Formula: C₁₈H₁₇NO₄

Purity: ≥ 99.0%

Color and Shape: White to almost white powder

Molecular weight: 311.34

Ref: 7W-GM7432

(-)-L-Alanine, N-FMOC protected

CAS: 35661-39-3

(-)-L-Alanine, N-FMOC protected

Formula: C₁₈H₁₇NO₄

Purity: 95%

Color and Shape: white powder

Molecular weight: 311.33g/mol

Ref: 54-OR18835

Fmoc-Ala-OH

CAS: 35661-39-3

M03347 - Fmoc-Ala-OH

Formula: C₁₈H₁₇NO₄

Purity: 98%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 311.337

Ref: 10-M03347

Fmoc-Ala-OH

CAS: 35661-39-3

Fmoc-Ala-OH is a protected alanine derivative used in solid-phase peptide synthesis, solar cell studies, and charge transfer and recombination.

Formula: C₁₈H₁₇NO₄

Purity: 99.57%

Molecular weight: 311.34

Ref: TM-T67563

Fmoc-Ala-OH

CAS: 35661-39-3

Fmoc-Ala-OH is a bioactive molecule with a molecular weight of 195.2 Daltons. It has been shown to have receptor activity and cyclic peptide properties. Fmoc-Ala-OH is soluble in chloroform and methanol, but insoluble in water. It can be used as a substrate for the chemical ligation reaction, which involves the joining of two peptides by forming an amide bond between their carboxyl groups. This process is known as "Fmoc chemistry". Fmoc-Ala-OH has also been shown to have anti-inflammatory effects in animal models of autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

Formula: C₁₈H₁₇NO₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 311.33 g/mol

Ref: 3D-FF16396

FMOC-L-Alanine extrapure, 99%

CAS: 35661-39-3

Formula: C₁₈H₁₇NO₄

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 311.34

Ref: SR-33213

N-Fmoc-L-alanine

Controlled Product

CAS: 35661-39-3

Applications N-Fmoc-L-alanine is an Fmoc-protected form of L-Alanine (A481500). L-Alanine used to make in-vivo measurement of glucose and alanine metabolism in studies of patients with diabetes. L-Alanine is a non-essential amino acid for human development and is one of the 20 amino acids encoded by the genetic code.
References Bier, D.M. et al.: Diabetes, 26, 1005 (1977); Capaldo, B. et al.: J. Clin. Endocrinol. Metab., 71, 1220 (1990); Giacca, A. et al.: Diabetes, 47, 1763 (1998);

Formula: C₁₈H₁₇NO₄

Color and Shape: Neat

Molecular weight: 311.33

Ref: TR-F619945

Fmoc-Ala-OH

CAS: 35661-39-3

Formula: C₁₈H₁₇NO₄

Molecular weight: 311.3

Ref: ST-EA-CP-L28010