CAS 35661-40-6

FMOC-L-phenylalanine

Description:

FMOC-L-phenylalanine, with the CAS number 35661-40-6, is a derivative of the amino acid phenylalanine, modified with a 9-fluorenylmethoxycarbonyl (FMOC) protecting group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group of phenylalanine during the coupling reactions. FMOC-L-phenylalanine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The FMOC group can be removed under mild basic conditions, allowing for the selective deprotection of the amino group when needed. This compound is valued for its stability and ease of handling, making it a popular choice in the synthesis of peptides and other complex organic molecules. Additionally, it retains the biological properties of phenylalanine, which is essential for various metabolic processes in living organisms.

Formula: C₂₄H₂₁NO₄

InChI: InChI=1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m0/s1

InChI key: InChIKey=SJVFAHZPLIXNDH-QFIPXVFZSA-N

SMILES: C(OC(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-phenylpropanoic acid
• (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-phenylpropanoic acid
• (S)-2-[9H-Fluoren-9-yl(methoxycarbonyl)amino]-3-phenylpropionic acid
• (S)-N-Fmoc-phenylalanine
• 226: PN: US20070042401 PAGE: 30 claimed protein
• 3-fenil-N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-alanina
• 917: PN: WO2006135786 PAGE: 59 claimed protein
• <span class="text-smallcaps">L</span>-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-<span class="text-smallcaps">L</span>-phenylalanine
• FMOC-L-phenylalanine
• Fmoc-phenylalanine
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-phenylalanine
• N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine
• N-(9-Fluorenylmethoxycarbonyl)phenylalanine
• N-9-Fluorenylmethoxycarbonylphenylalanine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-phenyl-L-alanin
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-phenylalanine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-phenyl-L-alanine
• N-[(9H-fluorene-9-ylmethoxy)carbonyl]-3-phenyl-L-alanine
• N-α-[[(9H-Fluoren-9-yl)methoxy]carbonyl]-<span class="text-smallcaps">L</span>-phenylalanine
• Nsc 334293

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine

CAS: 35661-40-6

Formula: C₂₄H₂₁NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 387.44

Ref: 3B-F0297

Fmoc-Phe-OH

CAS: 35661-40-6

Bachem ID: 4100450.

Formula: C₂₄H₂₁NO₄

Purity: 99.9%

Color and Shape: White Powder

Molecular weight: 387.44

Ref: 01-4100450

Fmoc-L-Phenylalanine

CAS: 35661-40-6

Formula: C₂₄H₂₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 387.4278

Ref: IN-DA00I72V

Fmoc-Phe-OH

CAS: 35661-40-6

Formula: C₂₄H₂₁NO₄

Purity: ≥ 99.0%

Color and Shape: White powder

Molecular weight: 387.44

Ref: 7W-GM5097

FMOC-Phe-OH

CAS: 35661-40-6

FMOC-Phe-OH

Formula: C₂₄H₂₁NO₄

Purity: 98.91%

Color and Shape: white powder

Molecular weight: 387.42784g/mol

Ref: 54-OR54571

Fmoc-Phe-OH

CAS: 35661-40-6

Fmoc-Phe-OH is a natural compound that has been shown to have antimicrobial properties. The biological properties of Fmoc-Phe-OH are not well understood, but it has been shown to have anticancer effects in some cases and to inhibit axonal growth when combined with the protein laminin. Fmoc-Phe-OH can be synthesized by the reaction of pheine with trifluoroacetic acid followed by treatment with h9c2 cells. The analytical method for determining the concentration of Fmoc-Phe-OH is based on intramolecular hydrogen exchange between hydrogen atoms on the amide group and hydrogens on neighboring methylene groups. This process releases heat, which is detected by a thermometer.
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Formula: C₂₄H₂₁NO₄

Purity: Min. 98.0 Area-%

Molecular weight: 387.44 g/mol

Ref: 3D-FLF-1730-PI

Fmoc-Phe-OH

CAS: 35661-40-6

Fmoc-Phe-OH is an amino acid derivative that has been used as a fluorescence probe for the detection of cervical cancer. Fmoc-Phe-OH binds to the DNA of human cells, and its fluorescence properties change when it is exposed to hydroxyl groups in blood serum. In addition, Fmoc-Phe-OH can be synthesized by solid phase synthesis and this process is monitored by silver ions. The fluorescence properties of Fmoc-Phe-OH are sensitive to changes in morphology and phase transition temperature.

Formula: C₂₄H₂₁NO₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 387.43 g/mol

Ref: 3D-FF15867

Fmoc-Phe-OH

CAS: 35661-40-6

M03370 - Fmoc-Phe-OH

Formula: C₂₄H₂₁NO₄

Purity: 99%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 387.435

Ref: 10-M03370

FMOC-L-Phenylalanine extrapure, 99%

CAS: 35661-40-6

Formula: C₂₄H₂₁NO₄

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 387.40

Ref: SR-39061