CymitQuimica logo

CAS 35661-60-0

:

Fmoc-leucine

Description:
Fmoc-leucine, or fluorenylmethoxycarbonyl-leucine, is a derivative of the amino acid leucine, commonly used in peptide synthesis and solid-phase peptide synthesis (SPPS). It features a protective Fmoc group that allows for selective deprotection during the synthesis process. The structure of Fmoc-leucine includes a fluorenylmethoxycarbonyl group attached to the amino group of leucine, which helps to stabilize the amino acid during synthesis and prevents unwanted reactions. Fmoc-leucine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its use in peptide synthesis is favored due to the ease of Fmoc group removal under mild basic conditions, allowing for the sequential addition of amino acids. Additionally, Fmoc-leucine retains the essential properties of leucine, such as its hydrophobic nature, making it valuable in the design of peptides with specific structural and functional characteristics.
Formula:C21H23NO4
InChI:InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1
InChI key:InChIKey=CBPJQFCAFFNICX-IBGZPJMESA-N
SMILES:C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:
  • (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-4-methylpentanoic acid
  • (S)-N-Fmoc-leucine
  • 217: PN: US20070042401 PAGE: 29 claimed protein
  • 908: PN: WO2006135786 PAGE: 58 claimed protein
  • <span class="text-smallcaps">L</span>-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • Fmoc-<span class="text-smallcaps">L</span>-Leucine
  • Fmoc-leucine
  • N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-leucine
  • N-(9-Fluorenylmethoxycarbonyl)-L-leucine
  • See more synonyms
Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 14 products.
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine

    CAS:
    Formula:C21H23NO4
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:353.42

    Ref: 3B-F0295

    1g
    22.00€
    5g
    28.00€
    25g
    59.00€
  • N-Fmoc-L-leucine, 98%

    CAS:
    <p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>
    Formula:C21H23NO4
    Purity:98%
    Color and Shape:White, Powder
    Molecular weight:353.42

    Ref: 02-B21040

    5g
    41.00€
    25g
    56.00€
  • Fmoc-Leu-OH

    CAS:
    <p>M03365 - Fmoc-Leu-OH</p>
    Formula:C21H23NO4
    Purity:98%
    Color and Shape:Solid, Crystalline Powder or Powder
    Molecular weight:353.418

    Ref: 10-M03365

    1g
    14.00€
    5g
    17.00€
    10g
    21.00€
    1kg
    252.00€
    25g
    24.00€
    100g
    54.00€
    500g
    175.00€
  • Fmoc-Leu-OH

    CAS:
    Fmoc-Leu-OH (NPC 15199, NSC 334290) showed anti-inflammatory activity. On histologic examination after administration of arachidonic acid, NPC 15199 was found to block the recruitment of neutrophils into the inflammatory site. Fmoc-L-leucine was effective in blocking antigen arthritis in rabbits.
    Formula:C21H23NO4
    Purity:99.95%
    Color and Shape:White
    Molecular weight:353.42

    Ref: 01-4003139

    25g
    94.00€
    100g
    142.00€
    500g
    541.00€
  • Fmoc-Leu-OH

    CAS:
    Formula:C21H23NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:353.4116

    Ref: IN-DA00I72W

    5g
    22.00€
    10g
    20.00€
    1kg
    228.00€
    25g
    28.00€
    50g
    41.00€
    5kg
    To inquire
    100g
    55.00€
    10kg
    To inquire
    250g
    115.00€
    25kg
    To inquire
    500g
    166.00€
  • Fmoc-Leu-OH

    CAS:
    Formula:C21H23NO4
    Purity:≥ 99.0%
    Color and Shape:White to almost white powder
    Molecular weight:353.42

    Ref: 7W-GM6129

    25g
    42.00€
    100g
    97.00€
    250g
    175.00€
  • NPC 15199

    CAS:
    <p>NPC 15199</p>
    Purity:≥98%
    Molecular weight:353.41g/mol

    Ref: 54-BUP18624

    500mg
    53.00€
  • NPC 15199

    CAS:
    <p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>
    Formula:C21H23NO4
    Purity:99.93% - 99.94%
    Color and Shape:White Crystalline Powder
    Molecular weight:353.41
  • L-Leucine, FMOC protected

    CAS:
    <p>L-Leucine, FMOC protected</p>
    Formula:C21H23NO4
    Purity:98%
    Color and Shape: white powder
    Molecular weight:353.41g/mol

    Ref: 54-OR0491

    500g
    223.00€
  • Fmoc-Leu-OH

    CAS:
    Formula:C21H23NO4
    Molecular weight:353.42

    Ref: 4Z-L-117005

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Fmoc-Leu-OH

    CAS:
    <p>Fmoc-Leu-OH is a fatty acid that contains a hydroxyl group. It is used in the synthesis of polymer drugs, especially sodium salt polymers. The activity of Fmoc-Leu-OH can be reversed with degarelix acetate, an irreversible inhibitor of ns3 protease. In addition to its use as an antidiabetic agent, Fmoc-Leu-OH has been shown to have immunomodulatory effects and antiinflammatory activity. In tumor treatment, Fmoc-Leu-OH has been shown to inhibit the growth of fat cells without affecting normal cells or causing any toxic side effects.</p>
    Formula:C21H23NO4
    Purity:Min. 98 Area-%
    Color and Shape:White Powder
    Molecular weight:353.41 g/mol

    Ref: 3D-FF15776

    1kg
    753.00€
    2kg
    1,090.00€
    5kg
    1,740.00€
    250g
    387.00€
    500g
    491.00€
  • Fmoc-Leu-OH

    CAS:
    <p>Fmoc-Leu-OH is a fatty acid that has been shown to be effective in treating inflammatory diseases such as skin cancer. It has also been shown to have neuroprotective and anti-inflammatory activities, which may be due to its ability to inhibit the nitrite levels in diabetic patients. Fmoc-Leu-OH has been shown to increase insulin sensitivity and decrease insulin resistance in diabetic patients. This drug may also have an effect on cancer by inhibiting the growth of tumor cells and inducing apoptosis.</p>
    Formula:C21H23NO4
    Purity:Min. 98.0 Area-%
    Molecular weight:353.41 g/mol

    Ref: 3D-FLL-1725-PI

    5g
    135.00€
    25g
    197.00€
    100g
    509.00€
  • FMOC-L-Leucine extrapure, 99%

    CAS:
    Formula:C21H23NO4
    Purity:min. 99%
    Color and Shape:White to Off white, Crystalline powder
    Molecular weight:353.40

    Ref: SR-99284

    25g
    37.00€
    100g
    79.00€
  • Fmoc-Leu-OH

    CAS:
    Formula:C21H23NO4
    Molecular weight:353.4

    Ref: ST-EA-CP-L28033

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire