CAS 35694-06-5

2,2′,3,4,4′,5-Hexachlorobiphenyl

Description:

2,2′,3,4,4′,5-Hexachlorobiphenyl, commonly referred to as PCB 153, is a polychlorinated biphenyl (PCB) compound characterized by the presence of six chlorine atoms attached to a biphenyl structure. This compound is part of a larger group of PCBs, which are synthetic organic chemicals known for their stability and resistance to degradation. PCB 153 is typically a colorless to light yellow solid and is insoluble in water but soluble in organic solvents. It exhibits high thermal stability and low volatility, making it persistent in the environment. Due to its lipophilic nature, it tends to bioaccumulate in the fatty tissues of living organisms, leading to potential toxic effects. PCBs, including PCB 153, have been associated with various health risks, including endocrine disruption and carcinogenic effects. As a result, their production and use have been heavily regulated or banned in many countries. Environmental monitoring and remediation efforts are ongoing to address the legacy of PCB contamination in ecosystems.

Formula: C₁₂H₄Cl₆

InChI: InChI=1S/C12H4Cl6/c13-5-1-2-6(8(14)3-5)7-4-9(15)11(17)12(18)10(7)16/h1-4H

InChI key: InChIKey=CKLLRBPBZLTGDJ-UHFFFAOYSA-N

SMILES: ClC1=C(C=C(Cl)C(Cl)=C1Cl)C2=C(Cl)C=C(Cl)C=C2

Synonyms:

• 1,1'-Biphenyl, 2,2',3,4,4',5-Hexachloro-
• 1,1′-Biphenyl, 2,2′,3,4,4′,5-hexachloro-
• 2,2',3,4,4',5-Pcb
• 2,2′,3,4,4′,5-Hexachloro-1,1′-biphenyl
• 2,2′,3,4,4′,5-Hexachlorobiphenyl
• 2,3,4,2′,4′,5-Hexachlorobiphenyl
• 2,3,4,5,2′,4′-Hexachlorobiphenyl
• 35694-06-5
• Pcb 137
• 2,2',3,4,4',5-Hexachlorobiphenyl

PCB No. 137 10 µg/mL in Isooctane

Controlled Product

CAS: 35694-06-5

Formula: C₁₂H₄Cl₆

Color and Shape: Single Solution

Molecular weight: 360.88

Ref: 04-L20013700IO

2,2',3,4,4',5-Hexachlorobiphenyl

Controlled Product

CAS: 35694-06-5

Formula: C₁₂H₄Cl₆

Color and Shape: Neat

Molecular weight: 360.88

Ref: TR-H290830

2,2',3,4,4',5-Hexachlorobiphenyl

Controlled Product

CAS: 35694-06-5

2,2',3,4,4',5-Hexachlorobiphenyl is a potent inhibitor of cancer cell growth and has been shown to induce apoptosis in Chinese hamster ovary cells. This compound also inhibits the activity of kinase inhibitors such as chloroquine and artesunate. It has been found in human urine samples and may be involved in the development of cancer. 2,2',3,4,4',5-Hexachlorobiphenyl has been identified as an analog of tumor-promoting compounds and may have potential as an anticancer agent. Further research is needed to fully understand its mechanism of action and potential therapeutic applications.

Formula: C₁₂H₄Cl₆

Purity: Min. 95%

Molecular weight: 360.9 g/mol

Ref: 3D-KBA69406