CAS 35699-00-4

5-Nitro-1,3-benzoxazole-2-carbonitrile

CAS: 35699-00-4

5-Nitro-1,3-benzoxazole-2-carbonitrile is a chemical compound that inhibits the uptake of drugs into cells. It is a selective inhibitor of the enzyme adenosine transporter (AT) which prevents the uptake of adenosine and other compounds into cells. The inhibition is reversible under conditions where ATP levels are low. 5-Nitro-1,3-benzoxazole-2-carbonitrile has been shown to be stable when exposed to human serum and can be used for sample preparation prior to analysis with high performance liquid chromatography (HPLC). This agent has also been shown to inhibit theophylline uptake in human erythrocytes, making it a useful tool for studying drug interactions. 5NBB also inhibits caffeine uptake in microspheres and can be used as an analytical reagent for determining caffeine content in beverages.

Formula: C₈H₃N₃O₃

Purity: Min. 95%

Molecular weight: 189.13 g/mol

Ref: 3D-KBA69900