CAS 357-70-0: (-)-Galantamine

Description: (-)-Galantamine is a naturally occurring alkaloid primarily derived from the bulbs and flowers of certain plants, such as snowdrop and daffodil. It is classified as a reversible inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the breakdown of the neurotransmitter acetylcholine. This characteristic makes (-)-Galantamine significant in the treatment of Alzheimer's disease and other cognitive disorders, as it helps to increase acetylcholine levels in the brain, thereby enhancing cholinergic function. The compound has a molecular formula of C17H21NO3 and features a bicyclic structure that includes a phenolic ring. It is known for its ability to cross the blood-brain barrier, which is essential for its therapeutic effects. Additionally, (-)-Galantamine exhibits various pharmacological properties, including neuroprotective and anti-inflammatory effects. Its stereochemistry is important for its biological activity, with the (-) enantiomer being the active form. The substance is typically administered in oral form and is well-tolerated, although it may have side effects such as nausea or dizziness in some individuals.

Formula: C₁₇H₂₁NO₃

InChI: InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1

InChI key: InChIKey=ASUTZQLVASHGKV-JDFRZJQESA-N

SMILES: OC1C=CC23C4=C(OC2C1)C(OC)=CC=C4CN(C)CC3

Synonyms:

• (-)-Galantamine
• (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, (4aS,6R,8aS)-
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, [4aS-(4aα,6β,8aR*)]-
• Brn 0093736
• Galantamin
• Galantamina
• Galanthamine
• Galanthamine Hydrochloride (1:1)
• Jilkon
• Lycoremin
• Lycoremine
• NSC 100058

Galantamine Hydrobromide

CAS: 1953-04-4 357-70-0

• Formula: C₁₇H₂₁NO₃·HBr
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 368.27

Galanthamine

CAS: 357-70-0

• Formula: C₁₇H₂₁NO₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 287.3535

(4As,6R,8As)-3-Methoxy-11-Methyl-5,6,9,10,11,12-Hexahydro-4Ah-Benzo[2,3]Benzofuro[4,3-Cd]Azepin-6-Ol

CAS: 357-70-0

• Purity: 98%
• Molecular weight: 287.35g/mol

Galanthamine

CAS: 357-70-0

• Purity: 99.87%
• Molecular weight: 287.35g/mol

Galanthamine

CAS: 357-70-0

• Formula: C₁₇H₂₁NO₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 287.36

Galanthamine

CAS: 357-70-0

• Formula: C₁₇H₂₁NO₃
• Purity: 95%~99%
• Molecular weight: 287.359

Galanthamine

CAS: 357-70-0

Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by …

• Formula: C₁₇H₂₁NO₃
• Purity: 98.03% - 99.87%
• Color and Shape: Off-White Solid
• Molecular weight: 287.35

Galanthamine

CAS: 357-70-0

Applications A selective acetylcholinesterase inhibitor. Useful for the treatment of Alzheimer's disease. Not a dangerous …

• Formula: C₁₇H₂₁NO₃
• Color and Shape: Neat
• Molecular weight: 287.35

(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol

CAS: 357-70-0

Please enquire for more information about (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol including the price, delivery time and more detailed …

• Formula: C₁₇H₂₁NO₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 287.35 g/mol