CAS 357166-30-4
:Pemetrexed disodium hydrate
Description:
Pemetrexed disodium hydrate is a chemotherapeutic agent primarily used in the treatment of certain types of cancer, particularly non-small cell lung cancer and mesothelioma. It functions as an antifolate, inhibiting multiple enzymes involved in folate metabolism, which is crucial for DNA synthesis and cell division. The substance is a white to off-white crystalline powder that is soluble in water, which facilitates its administration in clinical settings. Its molecular structure includes a disodium salt form, enhancing its solubility and stability in solution. Pemetrexed disodium hydrate is typically administered intravenously and is often used in combination with other chemotherapy agents to improve therapeutic efficacy. Side effects may include fatigue, nausea, and myelosuppression, necessitating careful monitoring during treatment. The compound's mechanism of action and its role in cancer therapy underscore its importance in oncology, making it a significant focus of research and clinical application.
Formula:(C20H19N5Na2O6)·5(H2O)
InChI:InChI=1/C20H21N5O6.2Na.H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;;1H2/q;2*+1;/p-2/t13-;;;/m0.../s1
InChI key:ZCTCZKWJFTYNMZ-WKUCUCPSSA-J
SMILES:C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]
Synonyms:- N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate
- Pemetrexed disodium 2.5H2O
- 2-[4-[2-(4-Amino-2-oxo-3,5,7-triazabicyclo[4.3.0]nona-3,8,10-trien-9-yl)ethyl]benzoyl]aminopentanedioic acid disodium salt hydrate
- Pemetrexed Disodium hemipenta hydrate
- Pemetrexed disodium hemipentahydrate
- Pemetrexed disodium hydrate
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Found 8 products.
Pemetrexed Disodium Hemipentahydrate
CAS:Formula:C40H38N10Na4O12·5H2OPurity:>97.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:1,032.84Pemetrexed disodium hemipenta hydrate
CAS:Pemetrexed disodium hemipenta hydrateFormula:C20H21N5O6·2NaH2OPurity:≥98%Molecular weight:518.43N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, sodium salt, hydrate (2:4:5)
CAS:Formula:C40H48N10Na4O17Purity:98%Color and Shape:SolidMolecular weight:1032.8250Pemetrexed disodium salt hydrate
CAS:Formula:C20H19N5Na2O6Purity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:471.37Pemetrexed Disodium Salt 2.5 Hydrate
CAS:Pemetrexed Disodium Salt 2.5 HydrateFormula:C40H48N10Na4O17Purity:99%Molecular weight:1032.84Pemetrexed disodium hemipenta hydrate
CAS:Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formula:C20H21N5O6·2NaH2OPurity:98.76%Color and Shape:SolidMolecular weight:518.43Pemetrexed disodium hemipenta hydrate
CAS:(S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid, sodium salt 2.5 hydrateFormula:C40H48N10Na4O17Purity:99%Molecular weight:1032.83
![N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid,…](https://static.cymitquimica.com/products/IN/thumb/DA00IKJ7.jpg)
