CAS 3573-90-8

(-)-Dehydrogriseofulvin

Description:

(-)-Dehydrogriseofulvin is a naturally occurring compound that belongs to the class of antifungal agents. It is derived from the fungus Penicillium griseofulvum and is known for its ability to inhibit fungal growth. The compound exhibits a complex molecular structure characterized by a fused ring system, which contributes to its biological activity. (-)-Dehydrogriseofulvin is typically used in the treatment of dermatophyte infections, particularly those affecting the skin, hair, and nails. Its mechanism of action involves disrupting the mitotic spindle formation in fungal cells, thereby preventing cell division and growth. The compound is often administered orally and has been studied for its pharmacokinetics, including absorption, distribution, metabolism, and excretion. Additionally, it has been noted for its potential side effects, which may include gastrointestinal disturbances and hypersensitivity reactions. Overall, (-)-Dehydrogriseofulvin represents an important therapeutic agent in the field of mycology and antifungal treatment.

Formula: C₁₇H₁₅ClO₆

InChI: InChI=1/C17H15ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h5-7H,1-4H3/t17-/m0/s1

InChI key: InChIKey=ISLYVROQSJYFAZ-KRWDZBQOSA-N

SMILES: O=C1[C@@]2(OC=3C1=C(OC)C=C(OC)C3Cl)C(OC)=CC(=O)C=C2C

Synonyms:

• (-)-Dehydrogriseofulvin
• (1′S)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-3,4′-dione
• (2S)-7-Chloro-3′,4,6-trimethoxy-5′-methylspiro[1-benzofuran-2,4′-cyclohexa-2,5-diene]-1′,3-dione
• Amudene
• Griseofulvin, dehydro-
• Spiro(benzofuran-2(3H),1'-(2,5)cyclohexadiene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (S)-
• Spiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-
• Spiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S)-
• Spiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (S)-
• (-)-Dehydro Griseofulvin
• Griseofulvin Dehydro Impurity
• Griseofulvin ImpuritⅡ (1'S)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-3,4'-dione)( (-)-Dehydro Griseofulvin)
• Spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S)-
• (2S)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohexa-2,5-diene]-1',3-dione
• Griseofulvin ImpuritⅡ (1’S)-7-Chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3H),1’-[2,5]cyclohexadiene]-3,4’-dione)( (-)-Dehydro Griseofulvin)
• (S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohexa[2,5]diene]-3,4'-dione

Dehydrogriseofulvin

CAS: 3573-90-8

Dehydrogriseofulvin is a natural product that can be used as a reference standard. The CAS number of Dehydrogriseofulvin is 3573-90-8.

Formula: C₁₇H₁₅ClO₆

Color and Shape: Solid

Molecular weight: 350.75

Ref: TM-T124964

(-)-Dehydro Griseofulvin

Controlled Product

CAS: 3573-90-8

Applications An impurity of Griseofulvin (G787500).
References Oda, T., et al.: Chem. Pharma. Bull., 34, 858 (1986),

Formula: C₁₇H₁₅ClO₆

Color and Shape: Neat

Molecular weight: 350.75

Ref: TR-D229940

Griseofulvin EP Impurity C

CAS: 3573-90-8

Formula: C₁₇H₁₅ClO₆

Molecular weight: 350.75

Ref: ST-EA-CP-G17003