CAS 35737-15-6: Fmoc-L-tryptophan

Description: Fmoc-L-tryptophan is a derivative of the amino acid tryptophan, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protective group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group of tryptophan during the coupling reactions. Fmoc-L-tryptophan is typically a white to off-white powder and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The Fmoc group can be removed under basic conditions, allowing for the subsequent coupling of the amino acid to other peptide fragments. This compound retains the essential properties of tryptophan, including its role as a precursor for serotonin and its involvement in protein synthesis. Additionally, it exhibits fluorescence properties due to the aromatic indole side chain, making it useful in various biochemical applications. Safety data should be consulted, as with all chemical substances, to ensure proper handling and usage.

Formula: C₂₆H₂₂N₂O₄

InChI: InChI=1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m0/s1

InChI key: InChIKey=MGHMWKZOLAAOTD-DEOSSOPVSA-N

SMILES: O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC(C(=O)O)CC4=CNC=5C=CC=CC54

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)propanoic acid
• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-3-(1H-indol-3-yl)propanoic acid
• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(1H-indol-3-yl)propanoic acid
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate
• (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-(1H-indol-3-yl)propionic acid
• <span class="text-smallcaps">L</span>-Tryptophan, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-<span class="text-smallcaps">L</span>-tryptophan
• Fmoc-L-tryptophan
• Fmoc-Trp-OH
• Fmoc-tryptophan
• N(alpha)-9-Fluorenylmethoxycarbonyl-L-tryptophan
• N-(9-Fluorenylmethoxycarbonyl)tryptophan
• N-(Fluorenyl-9-methoxycarbonyl)-terminated tryptophan
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tryptophan
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]tryptophan
• NSC 334295
• Nalpha-Fmoc-L-Tryptophan
• L-Tryptophan, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan

CAS: 35737-15-6

• Formula: C₂₆H₂₂N₂O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 426.47

Fmoc-Trp-OH

CAS: 35737-15-6

Bachem ID: 4003185.

• Formula: C₂₆H₂₂N₂O₄
• Purity: 99.3%
• Color and Shape: White
• Molecular weight: 426.47

L-Tryptophan, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 35737-15-6

• Formula: C₂₆H₂₂N₂O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 426.4639

Fmoc-Trp-OH

CAS: 35737-15-6

• Formula: C₂₆H₂₂N₂O₄
• Purity: 98%+
• Color and Shape: white to almost white crystal or powder
• Molecular weight: 426.46g/mol

Fmoc-Trp-OH

CAS: 35737-15-6

• Formula: C₂₆H₂₂N₂O₄
• Purity: ≥ 98.0%
• Color and Shape: White, faint yellow to faint brown powder
• Molecular weight: 426.48

Fmoc-Trp-OH

CAS: 35737-15-6

M03374 - Fmoc-Trp-OH

• Formula: C₂₆H₂₂N₂O₄
• Purity: 98%
• Color and Shape: Solid, Crystalline Powder or Powder
• Molecular weight: 426.47198486328125

Fmoc-L-Trp-OH

CAS: 35737-15-6

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• Formula: C₂₆H₂₂N₂O₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 426.46 g/mol

FMOC-L-Tryptophan extrapure, 99%

CAS: 35737-15-6

• Formula: C₂₆H₂₂N₂O₄
• Purity: min. 99%
• Color and Shape: White, Crystalline powder
• Molecular weight: 426.48

Nα-Fmoc-L-tryptophan-13C1115N2

CAS: 35737-15-6

• Formula: C₁₁C₁₅H₂₂N₂O₄
• Color and Shape: Neat
• Molecular weight: 439.37