CAS 357399-43-0

2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

Description:

2-(3-Chlorophenyl)-3,5,5-trimethylmorpholin-2-ol is a chemical compound characterized by its morpholine structure, which includes a hydroxyl group (-OH) and a chlorophenyl substituent. This compound features a morpholine ring that is substituted at the 2-position with a 3-chlorophenyl group, and at the 3 and 5 positions with three methyl groups, contributing to its steric bulk and potentially influencing its solubility and reactivity. The presence of the hydroxyl group suggests that it may exhibit properties typical of alcohols, such as hydrogen bonding capabilities, which can affect its boiling point and solubility in polar solvents. The chlorophenyl moiety may impart specific biological activity or influence the compound's interaction with other molecules. Overall, this compound's unique structure may lead to interesting applications in pharmaceuticals or agrochemicals, although specific biological or chemical properties would require further investigation through empirical studies.

Formula: C₁₃H₁₈ClNO₂

InChI: InChI=1/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3

SMILES: CC1C(c2cccc(c2)Cl)(O)OCC(C)(C)N1

Bupropion morpholinol

CAS: 357399-43-0

Formula: C₁₃H₁₈ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 255.7405

Ref: IN-DA00BXO3

Bupropion Morpholinol (Hydroxy Bupropion)

CAS: 357399-43-0

Formula: C₁₃H₁₈ClNO₂

Color and Shape: White To Off-White Solid

Molecular weight: 255.75

Ref: 4Z-B-052

Hydroxy Bupropion

CAS: 357399-43-0

Applications A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3’-chlorophenyl)-355-trimethylmorpholine). See US Pat. # 634.2496
References Hsyu, P-H., et al.: J. Clin. Pharm., 37, 737 (1997), Rotzinger, S., et al.: Cellular & Mol. Neurobiology, 19, 4, 427 (1999); US 6342496

Formula: C₁₃H₁₈ClNO₂

Color and Shape: Neat

Molecular weight: 255.74

Ref: TR-H830675

(±)-Hydroxybupropion

CAS: 357399-43-0

Hydroxybupropion is the hydroxy metabolite of buproprion. It is an atypical antidepressant that acts as a norepinephrine-dopamine reuptake inhibitor, and also has some nicotinic receptor activity. Hydroxybupropion is effective in the treatment of depression, with a lower incidence of side effects than standard antidepressants such as SSRIs. The drug has been shown to be effective in the treatment of ADHD and hyperactivity in children, but it is not approved for this use. Hydroxybupropion is mainly eliminated by hepatic metabolism and its plasma half-life is approximately twice that of buproprion, making it more suitable for once-daily administration.

Formula: C₁₃H₁₈ClNO₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 255.74 g/mol

Ref: 3D-FH23927

Hydroxy Bupropion-d8

Controlled Product

CAS: 357399-43-0

Formula: C₁₃D₈H₁₀ClNO₂

Color and Shape: Neat

Molecular weight: 263.79

Ref: TR-H830676

Hydroxy Bupropion-d6 Hydrochloride

Controlled Product

CAS: 357399-43-0

Formula: C₁₃H₁₂D₆ClNO₂·HCl

Color and Shape: Neat

Molecular weight: 298.24

Ref: TR-H830678

Bupropion Hydroxy Cyclic Impurity

CAS: 357399-43-0

Formula: C₁₃H₁₈ClNO₂

Molecular weight: 255.74

Ref: ST-EA-CP-B21013