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CAS 3575-80-2

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Melperone

Description:
Melperone is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the butyrophenone class of compounds and exhibits a unique pharmacological profile, characterized by its antagonistic activity at dopamine D2 receptors, which is a common mechanism among antipsychotics. Additionally, Melperone has affinity for serotonin receptors, contributing to its therapeutic effects and side effect profile. The substance is typically administered orally and is known for its relatively low incidence of extrapyramidal symptoms compared to other antipsychotics. Melperone is also recognized for its sedative properties, making it useful in managing agitation associated with psychotic disorders. Its chemical structure includes a butyrophenone moiety, which is essential for its activity. As with any medication, the use of Melperone should be carefully monitored due to potential side effects, including sedation, weight gain, and metabolic changes. Overall, Melperone represents a valuable option in the pharmacological management of certain psychiatric conditions.
Formula:C16H22FNO
InChI:InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3
InChI key:InChIKey=DKMFBWQBDIGMHM-UHFFFAOYSA-N
SMILES:C(CCCN1CCC(C)CC1)(=O)C2=CC=C(F)C=C2
Synonyms:
  • 1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone
  • 1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-
  • 4'-Fluor-4-(4-methylpiperidino)butyrophenon
  • 4'-Fluoro-4-(4-methylpiperidino)butyrophenone
  • 4-Fluoro-γ-(4-methylpiperidino)butyrophenone
  • Bunil
  • Buronil
  • Buronon
  • Butyrophenone, 4′-fluoro-4-(4-methylpiperidino)-
  • Fg 5111
  • See more synonyms
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