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CAS 3577-01-3

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cephaloglycin

Description:
Cephaloglycin is a semi-synthetic antibiotic belonging to the cephalosporin class, which is derived from the fungus Acremonium. It exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria, making it useful in treating various infections. The compound is characterized by its beta-lactam structure, which is essential for its mechanism of action, as it inhibits bacterial cell wall synthesis. Cephaloglycin is typically administered via injection and is known for its stability against certain beta-lactamases, enzymes produced by some bacteria that confer resistance to other antibiotics. Its pharmacokinetics involve good tissue penetration, allowing effective treatment of infections in various body sites. However, like other antibiotics, cephaloglycin may cause side effects, including allergic reactions and gastrointestinal disturbances. It is important to use this antibiotic judiciously to minimize the development of resistance. Overall, cephaloglycin represents an important tool in the arsenal against bacterial infections, particularly in cases where other antibiotics may be ineffective.
Formula:C18H19N3O6S
InChI:InChI=1/C18H19N3O6S/c1-9(22)27-7-11-8-28-17-13(16(24)21(17)14(11)18(25)26)20-15(23)12(19)10-5-3-2-4-6-10/h2-6,12-13,17H,7-8,19H2,1H3,(H,20,23)(H,25,26)/t12-,13-,17-/m1/s1
InChI key:InChIKey=FUBBGQLTSCSAON-PBFPGSCMSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](N)C3=CC=CC=C3)=O)C2=O)(SCC1COC(C)=O)[H]
Synonyms:
  • (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2R)-2-amino-2-phenylacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(aminophenylacetyl)amino]-8-oxo-, [6R-[6α,7β(R*)]]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-2-amino-2-phenylacetyl]amino]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-aminophenylacetyl]amino]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(2-amino-2-phenylacetamido)-3-(hydroxymethyl)-8-oxo-, acetate (ester), <span class="text-smallcaps">D</span>-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(2-amino-2-phenylacetamido)-3-(hydroxymethyl)-8-oxo-, acetate (ester), D-
  • 7-(2-<span class="text-smallcaps">D</span>-α-Aminophenylacetamido)cephalosporanic acid
  • 7-(2-D-α-Aminophenylacetamido)cephalosporanic acid
  • 7-(D-α-Aminophenylacetoamido)-cephalosporanic acid
  • <span class="text-smallcaps">D</span>-(-)-Cephaloglycin
  • See more synonyms
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Found 3 products.
  • Cefaloglycin

    CAS:
    <p>Cefaloglycin: oral nephrotoxic β-lactam antibiotic, active against Gram-positive cocci, impairs mitochondrial function.</p>
    Formula:C18H19N3O6S
    Color and Shape:Solid
    Molecular weight:405.42
  • Cephaloglycin

    CAS:
    <p>Stability Hygroscopic, Moisture Sensitive, Temperature Sensitive<br>Applications Cefaloglycin is a first-generation cephalosporin antibiotic.<br>References Yoshimura, F., et al.: Antimicrobial Agents Chemother., 27, 84 (1985); Daniel, H., et al.: J. Cin. Invest., 92, 2215 (1993)<br></p>
    Formula:C18H19N3O6S
    Color and Shape:Neat
    Molecular weight:405.43

    Ref: TR-C258000

    50mg
    298.00€
    500mg
    1,918.00€