
CAS 35775-82-7
:Leucomycin V, 12,13-epoxy-12,13-dihydro-, 3,4B-dipropanoate, (12S,13S)-
Description:
Leucomycin V, specifically the compound known as 12,13-epoxy-12,13-dihydro-, 3,4B-dipropanoate, (12S,13S)-, is an antibiotic belonging to the macrolide class of antibiotics. It is derived from the fermentation of the bacterium Streptomyces. This compound exhibits antibacterial properties, particularly effective against a range of Gram-positive bacteria. Its structure features a macrolide ring, which is characteristic of this class, along with an epoxy group and a dipropanoate moiety that contribute to its biological activity. The stereochemistry indicated by (12S,13S) suggests specific spatial arrangements of atoms that can influence its interaction with bacterial ribosomes, thereby inhibiting protein synthesis. Leucomycin V is often studied for its potential therapeutic applications and is of interest in the development of new antibiotics, especially in the context of rising antibiotic resistance. As with many antibiotics, its use must be carefully managed to minimize the development of resistance in target bacterial populations.
Formula:C41H67NO16
InChI:InChI=1S/C41H67NO16/c1-11-30(45)55-29-19-32(47)51-22(4)18-28-27(54-28)14-13-26(44)21(3)17-25(15-16-43)37(38(29)50-10)58-40-35(48)34(42(8)9)36(23(5)53-40)57-33-20-41(7,49)39(24(6)52-33)56-31(46)12-2/h13-14,16,21-29,33-40,44,48-49H,11-12,15,17-20H2,1-10H3
InChI key:InChIKey=FFXJTOKFQATYBI-UHFFFAOYSA-N
SMILES:O(C1C(OC)C(OC(CC)=O)CC(=O)OC(C)CC2C(C=CC(O)C(C)CC1CC=O)O2)C3C(O)C(N(C)C)C(OC4CC(C)(O)C(OC(CC)=O)C(C)O4)C(C)O3
Synonyms:- 4,17-Dioxabicyclo[14.1.0]heptadecane, leucomycin V deriv.
- Leucomycin V, 12,13-epoxy-12,13-dihydro-, 3,4B-dipropanoate, (12S,13S)-
- Antibiotic B 5050C
- Antibiotic YL 704C1
- Maridomycin III
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Maridomycin
CAS:Maridomycin is a macrolide antibiotic.Formula:C41H67NO16Color and Shape:SolidMolecular weight:829.978
