CAS 35795-16-5
:Trimazosin
Description:
Trimazosin is a pharmaceutical compound primarily classified as an alpha-1 adrenergic antagonist. It is utilized mainly in the treatment of hypertension and benign prostatic hyperplasia due to its ability to relax smooth muscle and dilate blood vessels, thereby reducing blood pressure and improving urinary flow. The chemical structure of trimazosin features a piperazine ring, which contributes to its pharmacological activity. It is typically administered in oral form and exhibits a moderate half-life, allowing for once or twice daily dosing. Trimazosin's mechanism of action involves selective blockade of alpha-1 adrenergic receptors, leading to vasodilation and decreased peripheral resistance. As with many medications, potential side effects may include dizziness, headache, and orthostatic hypotension. It is important for patients to be monitored for these effects, especially during the initiation of therapy. Overall, trimazosin represents a valuable option in the management of conditions related to elevated blood pressure and urinary obstruction.
Formula:C20H29N5O6
InChI:InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23)
InChI key:InChIKey=YNZXWQJZEDLQEG-UHFFFAOYSA-N
SMILES:O(C)C=1C2=C(C=C(OC)C1OC)C(N)=NC(=N2)N3CCN(C(OCC(C)(C)O)=O)CC3
Synonyms:- 1-Piperazinecarboxylic Acid, 4-(4-Amino-6,7,8-Trimethoxy-2-Quinazolinyl)-, 2-Hydroxy-2-Methylpropyl Ester
- 2-Hydroxy-2-Methylpropyl 4-(4-Amino-6,7,8-Trimethoxyquinazolin-2-Yl)Piperazine-1-Carboxylate
- 252-732-7
- 35795-16-5
- Cp 19106-1
- Supres
- Trimazosin
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Trimazosin
CAS:<p>Trimazosin, a quinazoline derivative and prazosin relative, lowers blood pressure by blocking alpha1-adrenoceptors.</p>Formula:C20H29N5O6Color and Shape:SolidMolecular weight:435.47
