CAS 35795-17-6

1-Piperazinecarboxylic acid, 4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester, hydrochloride (1:1)

Description:

1-Piperazinecarboxylic acid, 4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester, hydrochloride (1:1) is a complex organic compound characterized by its piperazine and quinazoline moieties, which contribute to its biological activity. The presence of multiple methoxy groups enhances its solubility and potential interactions with biological targets. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for pharmaceutical applications. The compound may exhibit properties such as antimicrobial or anticancer activity, owing to the structural features of the quinazoline ring, which is known for its diverse pharmacological effects. Additionally, the ester functional group suggests potential for hydrolysis, leading to the release of the active piperazinecarboxylic acid. Its molecular structure indicates that it may interact with various receptors or enzymes, making it a candidate for further research in medicinal chemistry. Overall, this compound's unique characteristics position it as a subject of interest in drug development and therapeutic applications.

Formula: C₂₀H₂₉N₅O₆·ClH

InChI: InChI=1S/C20H29N5O6.ClH/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5;/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23);1H

InChI key: InChIKey=KJZWJYNJYOFTNQ-UHFFFAOYSA-N

SMILES: O(C)C=1C2=C(C=C(OC)C1OC)C(N)=NC(=N2)N3CCN(C(OCC(C)(C)O)=O)CC3.Cl

Synonyms:

• 1-Piperazinecarboxylic acid, 4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester, hydrochloride (1:1)
• 1-Piperazinecarboxylic acid, 4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester, monohydrochloride
• 2-Hydroxy-2-Methylpropyl 4-(4-Amino-6,7,8-Trimethoxyquinazolin-2-Yl)Piperazine-1-Carboxylate Hydrochloride (1:1)
• Nsc 355084
• Trimazosin HCl
• Trimazosin hydrochloride
• Trimazosin hydrochloride anhydrous
• 2-Hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate monohydrochloride

Trimazosin Hydrochloride

Controlled Product

CAS: 35795-17-6

Applications Trimazosin is useful in therapy as potent antihypertensive agents.
References Andrews, C., et al.: Pharm. Res., 17, 639 (2000), Davis, A., et al.: Curr. Opin. Chem. Biol., 8, 378 (2004), Votano, J., et al.: J. Med. Chem., 49, 7169 (2006),

Formula: C₂₀H₃₀ClN₅O₆

Color and Shape: Neat

Molecular weight: 471.94

Ref: TR-T795515