CAS 358-23-6

Trifluoromethanesulfonic anhydride

Description:

Trifluoromethanesulfonic anhydride, also known as triflic anhydride, is a highly reactive chemical compound characterized by its strong electrophilic properties. It is a colorless to pale yellow liquid at room temperature and has a pungent odor. The compound is known for its ability to act as a powerful sulfonating agent, making it useful in various organic synthesis reactions, particularly in the preparation of sulfonic acids and esters. Its molecular structure features a trifluoromethyl group attached to a sulfonic anhydride moiety, which contributes to its high reactivity and stability under certain conditions. Trifluoromethanesulfonic anhydride is soluble in polar organic solvents but reacts vigorously with water, releasing triflic acid, a strong acid. Due to its corrosive nature, it requires careful handling and storage in inert atmospheres to prevent hydrolysis. Its applications extend to the pharmaceutical industry, materials science, and as a catalyst in various chemical reactions. Safety precautions are essential when working with this compound due to its toxic and corrosive properties.

Formula: C₂F₆O₅S₂

InChI: InChI=1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8

InChI key: InChIKey=WJKHJLXJJJATHN-UHFFFAOYSA-N

SMILES: S(OS(C(F)(F)F)(=O)=O)(C(F)(F)F)(=O)=O

Synonyms:

• Anhidrido Trifluorometanosulfonico
• Anhydride trifluoromethanesulfonique
• Methanesulfonic Anhydride, Trifluoro-
• Methanesulfonic acid, 1,1,1-trifluoro-, 1,1'-anhydride
• Perfluoromethanesulfonic anhydride
• Tf₂O
• Tirflic anhydride
• Triflate anhydride
• Triflic acid anhydride
• Triflic anhydride
• Trifluormethansulfonsaeureanhydrid
• Trifluoromethanesulfonic acid anhydride
• Trifluoromethanesulfonic anhydride
• Trifluoromethanesulfonic anyhydride
• Trifluoromethanesulfonyl anhydride
• Trifluoromethanesulfonyl trifluoromethanesulfonate
• Trifluoromethanesulphonic Anhydride
• Trifluoromethylsulfonic acid anhydride
• Trifluoromethylsulfonic anhydride
• Trifluoromethylsulfonyl trifluoromethanesulfonate
• Trifluoro methane Sulfonic Anhydride

Trifluoromethanesulfonic Anhydride

CAS: 358-23-6

Formula: C₂F₆O₅S₂

Purity: >98.0%(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 282.13

Ref: 3B-T1100

Trifluoromethanesulfonic anhydride, 98%

CAS: 358-23-6

Trifluoromethanesulfonic anhydride is used to convert phenols and imine into triflic ester and NTf group. It is a strong electrophile used for the introduction of triflyl group in chemical synthesis. It serves as a reagent in the preparation of alkyl and vinyl triflates, and for the stereoselective

Formula: C₂F₆O₅S₂

Purity: 98%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 282.13

Ref: 02-A11767

Trifluoromethanesulfonic anhydride

CAS: 358-23-6

Trifluoromethanesulfonic anhydride

Formula: C₂F₆O₅S₂

Purity: 99%

Color and Shape: clear.colourless liquid

Molecular weight: 282.13881g/mol

Ref: 54-PC7420

Trifluoromethanesulfonic anhydride

CAS: 358-23-6

Formula: C₂F₆O₅S₂

Purity: ≥ 99.0%

Color and Shape: Colourless to light yellow liquid

Molecular weight: 282.13

Ref: 7W-GK4778

Trifluoromethanesulfonic anhydride

CAS: 358-23-6

Formula: C₂F₆O₅S₂

Purity: 98.0%

Color and Shape: Liquid, Clear Liquid

Molecular weight: 282.13

Ref: 10-F007526

Trifluoromethanesulfonic anhydride

CAS: 358-23-6

Trifluoromethanesulfonic anhydride is more frequently known as triflic anhydride, since it derives from triflic acid. It is a versatile and strong electrophile used to insert the triflyl group (represented as Tf-) into chemical molecules (Ouyang, 2018). For example, trifluoromethane sulfonic anhydride interacts with some alkylsulfides to form stable salts that are used in the oxidation of alcohols. Moreover, trifluoromethane sulfonic anhydride has successfully shown high activity as a promoter in glycosylation reactions to obtain disaccharides (Tatai, 2007).

Formula: C₂F₆O₅S₂

Purity: Min. 95%

Color and Shape: Colorless Slightly Brown Clear Liquid

Molecular weight: 282.14 g/mol

Ref: 3D-FT01910

Trifluoromethanesulphonic anhydride, min. 97%

CAS: 358-23-6

Trifluoromethanesulphonic anhydride, min. 97%

Formula: (CF₃SO₂)₂O

Purity: min. 97%

Color and Shape: colorless liq.

Molecular weight: 282.13

Ref: 08-09-7420

Trifluoromethanesulfonic Anhydride

Controlled Product

CAS: 358-23-6

Stability Moisture Sensitive
Applications Trifluoromethanesulfonic Anhydride is a strong electrophile used in chemical synthesis for introducing the triflyl group.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cai, D. et al.: Org. Synth., 10, 112 (2004);

Formula: C₂F₆O₅S₂

Color and Shape: Neat

Molecular weight: 282.14

Ref: TR-T790520