CAS 35825-57-1
:Cryptotanshinone
Description:
Cryptotanshinone is a bioactive compound primarily derived from the roots of the plant Salvia miltiorrhiza, commonly known as Danshen. It belongs to the class of compounds known as tanshinones, which are known for their various pharmacological properties. Cryptotanshinone is characterized by its unique chemical structure, which includes a fused bicyclic system and several functional groups that contribute to its biological activity. This compound exhibits a range of potential therapeutic effects, including anti-inflammatory, antioxidant, and anticancer properties. Research has indicated that cryptotanshinone may influence various signaling pathways, making it a subject of interest in the field of medicinal chemistry. Additionally, it has shown promise in cardiovascular protection and neuroprotection. Its solubility and stability in different solvents can vary, which is important for its formulation in pharmaceutical applications. Overall, cryptotanshinone represents a significant area of study for its potential health benefits and therapeutic applications.
Formula:C19H20O3
InChI:InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
InChI key:InChIKey=GVKKJJOMQCNPGB-JTQLQIEISA-N
SMILES:O=C1C=2C(C3=C(C1=O)[C@@H](C)CO3)=CC=C4C2CCCC4(C)C
Synonyms:- (15R)-Cryptotanshinone
- (1R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethylphenanthro[1,2-b]furan-10,11-dione
- (1R)-1,6,6-Trimethyl-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-10,11-dione
- (1R)-1,6,6-trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione
- (R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione
- Cryototanshinone
- Cryptotanshinon
- Phenanthro[1,2-b]furan-10,11-dione, 1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (1R)-
- Phenanthro[1,2-b]furan-10,11-dione, 1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (R)-
- Tanshinone c
- Cryptotanshinone
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Found 13 products.
Cryptotanshinone
CAS:Formula:C19H20O3Purity:>97.0%(HPLC)Color and Shape:Orange to Brown powder to crystalMolecular weight:296.37Phenanthro[1,2-b]furan-10,11-dione,1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (R)-
CAS:Formula:C19H20O3Purity:98%Color and Shape:SolidMolecular weight:296.3603Cryptotanshinone
CAS:Cryptotanshinone9(CT), the major tanshinone isolated from Salvia miltiorrhiza Bunge, can suppress Bcl-2 expression and augment Fas sensitivity in DU145 cells, and JNK and p38 MAPK act upstream of Bcl-2 expression in Fas-treated DU145 cells; CT significantly blocks activation of these kinases and sensitizes several tumor cells to a broad range of anti-cancer agents; suggests that CT has therapeutic potential in the treatment of human prostate cancer.Formula:C19H20O3Purity:95%~99%Color and Shape:Red powderMolecular weight:296.366Cryptotanshinone
CAS:<p>Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.</p>Formula:C19H20O3Purity:97.94% - ≥95%Color and Shape:Orange Needle CrystalMolecular weight:296.36Cryptotanshinone
CAS:Formula:C19H20O3Purity:≥ 97.5%Color and Shape:Orange to brown powder or crystalsMolecular weight:296.36Cryptotanshinone
CAS:Oxygen-heterocyclic compoundFormula:C19H20O3Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:296.37Cryptotanshinone
CAS:Controlled Product<p>Applications Cryptotanshinone is an inhibitor of oncogenic protein tyrosine phosphatase SHP2.<br>References Liu, W., et. al.: J. Med. Chem., 56, 7212 (2013)<br></p>Formula:C19H20O3Color and Shape:NeatMolecular weight:296.36Cryptotanshinone
CAS:<p>Cryptotanshinone is a naturally occurring bioactive compound, which is an abietane diterpenoid sourced from the roots of *Salvia miltiorrhiza*, commonly known as Danshen. This compound exhibits a distinct mode of action characterized by its inhibition of the STAT3 signaling pathway, which is crucial in the regulation of gene expression involved in cell growth and survival. Furthermore, Cryptotanshinone demonstrates the ability to modulate various other molecular targets, such as the androgen receptor, rendering it valuable in the pharmacological landscape.</p>Formula:C19H20O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:296.36 g/mol
![Phenanthro[1,2-b]furan-10,11-dione,1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (R)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I73M.jpg&w=3840&q=75)
