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CAS 35834-26-5

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Rosaramicin

Description:
Rosaramicin is a chemical compound classified as a macrolide antibiotic, primarily known for its antibacterial properties. It is derived from the fermentation of specific strains of Streptomyces bacteria. The compound exhibits a broad spectrum of activity against various Gram-positive bacteria, making it useful in treating infections caused by these pathogens. Rosaramicin functions by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. Its structure features a large lactone ring, characteristic of macrolides, which is essential for its biological activity. The compound is typically administered in a clinical setting, and its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are crucial for determining its efficacy and safety profile. While it has shown promise in treating certain infections, the emergence of antibiotic resistance remains a concern, necessitating careful consideration of its use in clinical practice. Overall, Rosaramicin represents an important tool in the antibiotic arsenal, particularly for infections that are resistant to other treatments.
Formula:C31H51NO9
InChI:InChI=1S/C31H51NO9/c1-9-25-20(5)29-31(6,41-29)12-10-23(34)17(2)14-21(11-13-33)28(19(4)24(35)16-26(36)39-25)40-30-27(37)22(32(7)8)15-18(3)38-30/h10,12-13,17-22,24-25,27-30,35,37H,9,11,14-16H2,1-8H3/b12-10+/t17-,18-,19+,20-,21+,22+,24-,25-,27-,28-,29+,30+,31+/m1/s1
InChI key:InChIKey=IUPCWCLVECYZRV-JZMZINANSA-N
SMILES:C[C@]1/2[C@@](O1)([C@H](C)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C2)[H]
Synonyms:
  • 3-Ethyl-7-Hydroxy-2,8,12,16-Tetramethyl-5,13-Dioxo-10-(2-Oxoethyl)-4,17-Dioxabicyclo[14.1.0]Heptadec-14-En-9-Yl 3,4,6-Trideoxy-3-(Dimethylamino)Hexopyranoside
  • 4,17-Dioxabicyclo[14.1.0]heptadecane, cirramycin A<sub>1</sub> deriv.
  • 4′-Deoxycirramycin A<sub>1</sub>
  • Antibiotic 67-694
  • Antibiotic M 4365A<sub>2</sub>
  • Antibiotic T 1124C
  • Cirramycin A<sub>1</sub>, 4′-deoxy-
  • Juvenimicin A<sub>3</sub>
  • M 4365A<sub>2</sub>
  • NSC 175150
  • See more synonyms
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