CAS 35838-58-5

Etazolate, Hydrochloride

Description:

Etazolate hydrochloride is a chemical compound primarily recognized for its use in pharmacology, particularly as an anxiolytic and sedative agent. It belongs to the class of compounds known as benzodiazepines, which are characterized by their ability to modulate the activity of neurotransmitters in the brain, particularly gamma-aminobutyric acid (GABA). The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. Etazolate is known for its relatively rapid onset of action and is often studied for its effects on anxiety and sleep disorders. In terms of physical properties, it typically appears as a white to off-white crystalline powder. Its solubility profile indicates that it is soluble in water and various organic solvents, which is advantageous for its formulation in different dosage forms. As with many pharmacological agents, the safety profile, potential side effects, and interactions with other medications are important considerations in its use. Overall, Etazolate hydrochloride represents a significant compound in the realm of therapeutic agents targeting anxiety and related conditions.

Formula: C₁₄H₂₀ClN₅O₂

InChI: InChI=1/C14H19N5O2.ClH/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2;/h7-8H,5-6H2,1-4H3,(H,15,18);1H

SMILES: CCn1c2c(cn1)c(c(cn2)C(=O)OCC)NN=C(C)C.Cl

Synonyms:

• Etazolate hydrochloride [USAN]
• 1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester, monohydrochloride
• Etazolate HCl
• Ethyl 1-ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo(3,4-b)pyridine-5-carboxylate monohydrochloride
• Nsc 163611
• Sq 20009
• Unii-7Yo3254Y6B
• ethyl 1-ethyl-4-[2-(propan-2-ylidene)hydrazinyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylate hydrochloride (1:1)
• Etazolate hydrochloride

Etazolate hydrochloride

CAS: 35838-58-5

Formula: C₁₄H₁₈N₅O₂·HCl

Molecular weight: 324.79

Ref: 7W-GL9276

Etazolate Hydrochloride

Controlled Product

CAS: 35838-58-5

Formula: C₁₄H₁₉N₅O₂·ClH

Color and Shape: Neat

Molecular weight: 325.794

Ref: TR-E889255

Etazolate hydrochloride

CAS: 35838-58-5

Etazolate hydrochloride is a small molecule that inhibits the activity of cyclase, the enzyme which catalyzes the conversion of ATP to cAMP. Inhibition of cyclase prevents the activation of protein kinases and phosphatases, which are important for cellular signaling. Etazolate hydrochloride has been shown to inhibit neuronal death in a model system and may have potential as a treatment for neurodegenerative diseases such as Alzheimer’s or Parkinson’s disease. Etazolate hydrochloride also inhibits bowel disease in mice by blocking the production of inflammatory molecules such as prostaglandin E2 and nitric oxide. It has been shown to have anti-inflammatory effects on leukemic mice by inhibiting cyclic nucleotide phosphodiesterases (PDE).

Formula: C₁₄H₂₀ClN₅O₂

Purity: Min. 95%

Molecular weight: 325.79 g/mol

Ref: 3D-KBA83858