CAS 35838-63-2

Clocoumarol

Description:

Clocoumarol is an anticoagulant medication that belongs to the coumarin class of compounds. It is primarily used in the prevention and treatment of thromboembolic disorders. The substance functions by inhibiting vitamin K epoxide reductase, which is essential for the synthesis of vitamin K-dependent clotting factors in the liver. This action leads to a decrease in blood coagulation, thereby reducing the risk of blood clots. Clocoumarol is characterized by its relatively long half-life, which allows for once-daily dosing in clinical settings. It is typically administered orally and is metabolized in the liver, with its pharmacokinetics influenced by various factors, including genetic variations in metabolic enzymes. Side effects may include bleeding complications, which necessitate careful monitoring of coagulation parameters during treatment. As with other anticoagulants, it is crucial to consider potential interactions with other medications and dietary vitamin K intake, as these can significantly affect its efficacy and safety profile.

Formula: C₂₁H₂₁ClO₃

InChI: InChI=1/C21H21ClO3/c1-2-5-16(15-10-8-14(9-11-15)12-13-22)19-20(23)17-6-3-4-7-18(17)25-21(19)24/h3-4,6-11,16,24H,2,5,12-13H2,1H3

InChI key: InChIKey=XEBSDNCEYSPGIU-UHFFFAOYSA-N

SMILES: CCCC(c1ccc(cc1)CCCl)c1c(=O)c2ccccc2oc1O

Synonyms:

• 2H-1-Benzopyran-2-one, 3-(1-(4-(2-chloroethyl)phenyl)butyl)-4-hydroxy-
• 3-(1-(4-(2-Chloroethyl)phenyl)butyl)-4-hydroxy-2H-1-benzopyran-2-one
• 3-(p-(2-Chloroethyl)-alpha-propylbenzyl)-4-hydroxycoumarin
• 3-[1-(p-Chlorethylphenyl)butyl]-4-hydroxycoumarin
• 3-{1-[4-(2-chloroethyl)phenyl]butyl}-2-hydroxy-4H-chromen-4-one
• 3[1-[p-(2-Chloroethyl)phenyl]butyl]-4-hydroxycoumarin
• Brn 1264788
• Clocoumarol [INN]
• Clocoumarolum
• Clocoumarolum [INN-Latin]
• Clocumarol
• Clocumarol [INN-Spanish]
• Coumarin, 3-(p-(2-chloroethyl)-alpha-propylbenzyl)-4-hydroxy-
• Db 112
• Unii-M9K14Z7S3L

Clocoumarol

Controlled Product

CAS: 35838-63-2

Formula: C₂₁H₂₁ClO₃

Color and Shape: Neat

Molecular weight: 356.843

Ref: TR-C583835

Clocoumarol

CAS: 35838-63-2

Clocoumarol is an anticoagulant that prevents blood clotting. It also can inhibit the dilatation of the spleen and the congestion of lymph nodes.

Formula: C₂₁H₂₁ClO₃

Color and Shape: Solid

Molecular weight: 356.84

Ref: TM-T23898