CAS 35842-45-6

Tiglylglycine

Description:

Tiglylglycine, with the CAS number 35842-45-6, is an amino acid derivative characterized by its structure, which includes a glycine moiety and a tiglyl group. This compound is notable for its potential applications in biochemical research and as a building block in organic synthesis. Tiglylglycine is typically a white to off-white crystalline solid, and it is soluble in polar solvents, which facilitates its use in various chemical reactions. The presence of both an amino group and a carboxylic acid group in its structure allows it to participate in typical amino acid reactions, such as peptide bond formation. Additionally, its unique tiglyl substituent may impart specific biological activities or properties, making it of interest in pharmacological studies. As with many amino acid derivatives, it is important to handle tiglylglycine with care, following appropriate safety protocols, as its reactivity and biological effects can vary depending on the context of its use.

Formula: C₇H₁₁NO₃

InChI: InChI=1S/C7H11NO3/c1-3-5(2)7(11)8-4-6(9)10/h3H,4H2,1-2H3,(H,8,11)(H,9,10)/b5-3+

InChI key: InChIKey=WRUSVQOKJIDBLP-HWKANZROSA-N

SMILES: C(NCC(O)=O)(/C(=C/C)/C)=O

Synonyms:

• Glycine, N-(2-methyl-1-oxo-2-butenyl)-, (E)-
• Glycine, N-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-
• Glycine, N-[(2E)-2-methyl-1-oxo-2-butenyl]-
• N-Tigloylglycine
• N-Tiglylglycine
• N-[(2E)-2-Methyl-1-oxo-2-buten-1-yl]glycine
• N-[(2E)-2-methylbut-2-enoyl]glycine
• Tiglylglycine

N-Tigloylglycine

CAS: 35842-45-6

Formula: C₇H₁₁NO₃

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 157.17

Ref: 3B-T1260

N-[(2E)-2-Methyl-1-oxo-2-buten-1-yl]glycine

CAS: 35842-45-6

Formula: C₇H₁₁NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 157.1671

Ref: IN-DA003TDV

(E)-2-(2-Methylbut-2-enamido)acetic acid

CAS: 35842-45-6

(E)-2-(2-Methylbut-2-enamido)acetic acid

Purity: 97%

Molecular weight: 157.17g/mol

Ref: 54-OR1031014

Tiglyl Glycine

CAS: 35842-45-6

Formula: C₇H₁₁NO₃

Purity: ≥ 97.5%

Color and Shape: White to off-white powder

Molecular weight: 157.17

Ref: 7W-GM1456

Tiglylglycine

CAS: 35842-45-6

Formula: C7H11NO3

Purity: >98%

Color and Shape: Liquid

Molecular weight: 157.17

Ref: 48-41-1500

Tiglyl Glycine-13C2,15N

CAS: 35842-45-6

Applications Tiglyl Glycine-13C2,15N is a labelled derivative of Tiglyl Glycine (T440100).

Formula: C₂C₅H₁₁₁₅NO₃

Color and Shape: Neat

Molecular weight: 160.146

Ref: TR-T440102

Tiglyl Glycine

CAS: 35842-45-6

Applications A metabolite a Isoleucine.
References Bennett, M., et al.: Clin. Chem., 40, 1879 (1994), Gibson, K., et al.: Pediatr. Res., 47, 830 (2000), Sutton, V., et al.: J. Inherit. Metab. Dis., 26, 69 (2003),

Formula: C₇H₁₁NO₃

Color and Shape: Off-White

Molecular weight: 157.17

Ref: TR-T440100

Tiglyl glycine

CAS: 35842-45-6

Tiglyl glycine is a drug that belongs to the class of non-competitive inhibitors of the α1 subunit of mitochondrial polymerase. It has been shown to inhibit the synthesis of malonic acid, which is a metabolic product, and tiglic acid, which is an intermediate in energy metabolism. Tiglyl glycine has been shown to have therapeutic effects against infectious diseases and metabolic disorders such as methyl ethyl malonic aciduria, with symptoms including brain dysfunction, vomiting, and weight loss. Tiglyl glycine inhibits the production of methyl ethylmalonic acid from propionate in patients with this disorder. Tiglyl glycine also has been shown to be effective in reducing body mass index and human serum levels of malonic acid in obese patients.

Formula: C₇H₁₁NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 157.17 g/mol

Ref: 3D-FT28274

N-TIGLOYLGLYCINE

CAS: 35842-45-6

Formula: C₇H₁₁NO₃

Purity: 97%

Molecular weight: 157.169

Ref: 10-F470204