CAS 35846-53-8

MTS

Description:

MTS, or 1-Methyl-2-thiourea, is a chemical compound characterized by its thiourea structure, which includes a methyl group attached to the nitrogen atom. It is primarily recognized for its role as a reagent in various chemical reactions, particularly in organic synthesis and as a building block in the preparation of other compounds. MTS is known for its ability to act as a nucleophile due to the presence of the thiol group, making it useful in the formation of carbon-sulfur bonds. Additionally, it exhibits properties that can influence biological systems, which has led to its investigation in pharmacological contexts. MTS is typically handled with care, as it may pose health risks, including potential toxicity. Its solubility in water and organic solvents allows for versatile applications in laboratory settings. As with any chemical, proper safety protocols should be followed when handling MTS to mitigate any risks associated with exposure.

Formula: C₃₄H₄₆ClN₃O₁₀

InChI: InChI=1S/C34H46ClN3O10/c1-18-11-10-12-26(45-9)34(43)17-25(46-32(42)36-34)19(2)30-33(5,48-30)27(47-31(41)20(3)37(6)21(4)39)16-28(40)38(7)23-14-22(13-18)15-24(44-8)29(23)35/h10-12,14-15,19-20,25-27,30,43H,13,16-17H2,1-9H3,(H,36,42)/b12-10+,18-11+/t19-,20+,25+,26-,27+,30+,33+,34+/m1/s1

InChI key: InChIKey=WKPWGQKGSOKKOO-RSFHAFMBSA-N

SMILES: C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]

Synonyms:

• (2'R,3beta,4beta,6beta,7beta,9beta)-maytansine
• (3Beta,4Beta,6Beta,7Beta,9Beta)-Maytansine
• (4beta,11E,13E)-maytansine
• 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1^10,14.0^3,5]hexacosane, maytansine deriv.
• <span class="text-smallcaps">L</span>-Alanine, N-acetyl-N-methyl-, 11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1^10,14.0^3,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl ester, [1S-(1R*,2S*,3R*,5R*,6R*,16E,18E,20S*,21R*)]-
• Brn 5417399
• L-Alanine, N-acetyl-N-methyl-, 11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo(19.3.1.110,14.03,5)hexacosa-10,12,14(26),16,18-pentaen-6-yl ester, (1S-(1R*,2S*,3R*,5R*,6R*,16E,18E,20S*,21R*))-
• Maitansina
• Maitansina [INN-Spanish]
• Maitansinum
• Maitansinum [INN-Latin]
• Maysanine
• Maytansin
• Maytansine
• Maytansine [USAN]
• N-Acetyl-N-methyl-<span class="text-smallcaps">L</span>-alanine [1S-(1R*,2S*,3R*,5R*,6R*,16E,18E,20S*,21R*)]-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1^10,14.0^3,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl ester
• N-Acetyl-N-methyl-L-alanine(1S-(1R*,2S*,3R*,5R*,6R*,16E,18E,20S*,21R*))-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethy-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo(19.3.1.1(sup 10,14).0(sup 3,5))hexacosa-10,12,14(26),16,18-pentaen-6-yl ester
• Nsc 153858
• Unii-14083Fr882

Maytansine

CAS: 35846-53-8

Formula: C₃₄H₄₆ClN₃O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 692.1961

Ref: IN-DA003RGH

(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-Chloro-14-Hydroxy-85,14-Dimethoxy-33,2,7,10-Tetramethyl-12,6-Dioxo-7-Aza-1(6,4)-Oxazinana-3(2,3)-Oxirana-8(1,3)-Benzenacyclotetradecaphane-10,12-Dien-4-Yl N-Acet

CAS: 35846-53-8

(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-Chloro-14-Hydroxy-85,14-Dimethoxy-33,2,7,10-Tetramethyl-12,6-Dioxo-7-Aza-1(6,4)-Oxazinana-3(2,3)-Oxirana-8(1,3)-Benzenacyclotetradecaphane-10,12-Dien-4-Yl N-Acet

Purity: 98%

Molecular weight: 692.2g/mol

Ref: 54-OR1023838

Maytansine

CAS: 35846-53-8

Maytansine

Purity: ≥98%

Molecular weight: 692.2g/mol

Ref: 54-BUP06776

Maytansine

CAS: 35846-53-8

Formula: C₃₄H₄₆ClN₃O₁₀

Molecular weight: 692.21

Ref: 4Z-M-116001

Maytansine

CAS: 35846-53-8

Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding

Formula: C₃₄H₄₆ClN₃O₁₀

Purity: 99.32% - 99.62%

Color and Shape: Powder Powder

Molecular weight: 692.2

Ref: TM-T21351

Maytansine

Controlled Product

CAS: 35846-53-8

Stability Light Sensitive
Applications Maytansine inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014)

Formula: C₃₄H₄₆ClN₃O₁₀

Color and Shape: Neat

Molecular weight: 692.2

Ref: TR-M197940