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CAS 35850-13-6

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15-Keto-PGF2α

Description:
15-Keto-PGF2α, also known as 15-keto-prostaglandin F2α, is a metabolite of prostaglandin F2α (PGF2α), which is a naturally occurring prostaglandin involved in various physiological processes, including the regulation of smooth muscle contraction and modulation of inflammatory responses. This compound is characterized by its ketone functional group at the 15 position of the prostaglandin structure, which distinguishes it from its parent compound. It exhibits biological activity similar to PGF2α but with altered potency and receptor interactions. 15-Keto-PGF2α is typically found in biological fluids and tissues, where it plays a role in reproductive physiology and may influence processes such as ovulation and parturition. Its chemical structure includes a cyclopentane ring and multiple functional groups, contributing to its reactivity and interactions with specific receptors. The compound is of interest in pharmacological research and may have implications in therapeutic applications related to reproductive health and inflammation.
Formula:C20H32O5
InChI:InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,16-19,22-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t16-,17-,18+,19-/m1/s1
InChI key:InChIKey=LOLJEILMPWPILA-AMFHKTBMSA-N
SMILES:C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/C(CCCCC)=O)[C@H](O)C[C@@H]1O
Synonyms:
  • 15-Dehydroprostaglandin F2α
  • Prosta-5,13-dien-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,9α,11α,13E)-
  • 15-Keto PGF2α
  • 15-Ketoprostaglandin F2α
  • (5Z,9α,11α,13E)-9,11-Dihydroxy-15-oxoprosta-5,13-dien-1-oic acid
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