CAS 35865-33-9

Dianemycin

Description:

Dianemycin, with the CAS number 35865-33-9, is a chemical compound that belongs to the class of antibiotics known as macrolides. It is produced by certain strains of the bacterium Streptomyces, which are known for their ability to synthesize a variety of bioactive compounds. Dianemycin exhibits antibacterial properties, making it effective against a range of Gram-positive bacteria. Its mechanism of action typically involves inhibiting protein synthesis by binding to the bacterial ribosome, thereby disrupting the growth and reproduction of the bacteria. In addition to its antibacterial activity, dianemycin may also possess antifungal and antitumor properties, although research in these areas is ongoing. The compound's structure features a large lactone ring, characteristic of macrolides, which contributes to its biological activity. As with many antibiotics, the potential for resistance development is a concern, necessitating careful consideration of its use in clinical settings. Further studies are essential to fully understand its pharmacological profile and potential therapeutic applications.

Formula: C₄₇H₇₈O₁₄

InChI: InChI=1S/C47H78O14/c1-24(40(50)25(2)18-28(5)43(51)52)17-26(3)41-31(8)34(49)22-45(59-41)16-15-44(11,61-45)38-21-36(56-39-14-13-35(54-12)33(10)55-39)32(9)47(58-38)30(7)20-37(57-47)42-27(4)19-29(6)46(53,23-48)60-42/h17,25-39,41-42,48-49,53H,13-16,18-23H2,1-12H3,(H,51,52)/b24-17+/t25-,26+,27+,28+,29-,30+,31-,32-,33-,34+,35+,36+,37-,38-,39-,41-,42+,44+,45-,46+,47+/m1/s1

InChI key: InChIKey=FELYAZAWTURXNF-KWJIWYEDSA-N

SMILES: C[C@H]1[C@]2(O[C@](C[C@@H]1O[C@H]3O[C@H](C)[C@@H](OC)CC3)([C@@]4(C)O[C@@]5(CC4)O[C@]([C@H](/C=C(/C([C@@H](C[C@@H](C(O)=O)C)C)=O)\C)C)([C@H](C)[C@@H](O)C5)[H])[H])O[C@](C[C@@H]2C)([C@]6(O[C@](CO)(O)[C@H](C)C[C@@H]6C)[H])[H]

Synonyms:

• Stereoisomer of 8-[9-hydroxy-2,4′,8,10′-tetramethyl-2′-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9′-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy][2,7′-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-6-nonenoic acid
• 6-Nonenoic acid, 8-[(2S,2′R,4′S,5R,5′S,7R,7′R,8R,9S,9′S,10′R)-9-hydroxy-2,4′,8,10′-tetramethyl-2′-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9′-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy][2,7′-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-, (2S,4R,6E,8S)-
• (2S,4R,6E,8S)-8-[(2S,2′R,4′S,5R,5′S,7R,7′R,8R,9S,9′S,10′R)-9-Hydroxy-2,4′,8,10′-tetramethyl-2′-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9′-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy][2,7′-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-6-nonenoic acid
• Dianemycin
• 6-Nonenoic acid, 8-[9-hydroxy-2,4′,8,10′-tetramethyl-2′-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9′-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy][2,7′-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-, [2S-[2α[2′S*,4′R*,5′R*,7′S*[2R*,5S*,7S*(2R*,4S*,6E,8R*),8S*,9R*],9′R*(2R*,5R*,6S*),10′S*],3β,5β,6β]]-

Dianemycin

CAS: 35865-33-9

Dianemycin

Purity: ≥98%

Molecular weight: 867.11g/mol

Ref: 54-BUP16333

Dianemycin

CAS: 35865-33-9

Dianemycin (Nanchangmycin (free acid)) is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria.

Formula: C₄₇H₇₈O₁₄

Purity: 98% - 99.86%

Color and Shape: Solid

Molecular weight: 867.11

Ref: TM-T8504