CAS 35891-70-4: (+)-Myriocin
Description:(+)-Myriocin, also known as ISP-1, is a natural product derived from the fungus *Myriococcum albomyces*. It is classified as a sphingolipid synthesis inhibitor and is notable for its role in the study of sphingolipid metabolism. The compound exhibits a complex structure characterized by a long aliphatic chain and multiple functional groups, which contribute to its biological activity. (+)-Myriocin is primarily recognized for its immunosuppressive properties, making it of interest in pharmacological research, particularly in the context of transplant rejection and autoimmune diseases. It functions by inhibiting serine palmitoyltransferase, an enzyme crucial for the biosynthesis of sphingolipids, thereby affecting cell signaling and proliferation. In addition to its therapeutic potential, (+)-Myriocin has been studied for its effects on various cellular processes, including apoptosis and inflammation. Its unique properties and mechanisms of action continue to be explored in both basic and applied research settings.
Formula:C21H39NO6
InChI:InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m1/s1
InChI key:InChIKey=ZZIKIHCNFWXKDY-GNTQXERDSA-N
SMILES:O=C(O)C(N)(CO)C(O)C(O)CC=CCCCCCCC(=O)CCCCCC
- Synonyms:
- (+)-Myriocin
- (2R,3S,4S,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-icosenoic acid
- (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid
- (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
- (E,2R,3S,4S)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-icos-6-enoic acid
- 6-Eicosenoic acid, 2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-, (2S,3R,4R,6E)-
- 6-Eicosenoic acid, 2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-, [2S-(2R*,3S*,4S*,6E)]-
- 6-eicosenoic acid, 2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-, (2R,3S,4S,6E)-
- Isp-I
- NSC 177379
- See more synonyms
- Thermozymocidin

(E,2R,3S,4S)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
Ref: IN-DA00I743
1mg | 118.00 € | ||
5mg | 242.00 € | ||
25mg | To inquire |

Myriocin
Ref: TM-T16165
2mg | 605.00 € | ||
5mg | 1,088.00 € |

Myriocin from Mycelia sterilia
Ref: 54-BIM1005
10mg | 132.00 € | ||
25mg | 269.00 € | ||
50mg | 464.00 € | ||
100mg | 818.00 € | ||
250mg | 1,618.00 € | ||
500mg | 2,904.00 € |

Myriocin
Ref: 7W-GL9729
5mg | 110.00 € | ||
10mg | 238.00 € | ||
25mg | 378.00 € |

Myriocin
Ref: 3D-AM57735
5mg | 185.00 € | ||
10mg | 286.00 € | ||
25mg | 531.00 € | ||
50mg | 880.00 € | ||
100mg | 1,421.00 € |