CAS 35892-95-6

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt

Formula: C₁₀H₁₅N₄O₁₃P₃·4Na

Synonyms:

• 9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt
• Purine riboside-5'-O-triphosphate (sodium salt)

Purine riboside-5'-O-triphosphate sodium

CAS: 35892-95-6

Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.

Formula: C₁₀H₁₁N₄Na₄O₁₃P₃

Color and Shape: Solid

Molecular weight: 580.09

Ref: TM-T203586