CAS 359-84-2

2H-1,2,4-Benzothiadiazine, 3,4-dihydro-, 1,1-dioxide

Description:

2H-1,2,4-Benzothiadiazine, 3,4-dihydro-, 1,1-dioxide, commonly known as benzothiadiazine dioxide, is a heterocyclic compound characterized by its bicyclic structure that includes both a benzene ring and a thiadiazine moiety. This compound is typically a white to off-white solid and is known for its stability under standard conditions. It exhibits moderate solubility in polar solvents, which can facilitate its use in various chemical applications. The presence of the sulfonyl group contributes to its reactivity, making it a useful intermediate in organic synthesis. Additionally, this compound has been studied for its potential pharmacological properties, particularly in the field of diuretics and antihypertensives. Its unique structure allows for interactions with biological targets, which may lead to therapeutic effects. Safety data indicates that, like many chemical substances, it should be handled with care, following appropriate safety protocols to mitigate any risks associated with exposure.

Formula: C₇H₈N₂O₂S

InChI: InChI=1/C7H8N2O2S/c10-12(11)7-4-2-1-3-6(7)8-5-9-12/h1-4,8-9H,5H2

InChI key: InChIKey=OKXYPUDKVYVJDI-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(=CC=CC2)NCN1

Synonyms:

• 3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
• 3,4-Dihydro-1,2,4-benzothiadiazine 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine, 3,4-dihydro-, 1,1-dioxide
• 3,4-Dihydro-2H-1,2,4-benzothiadiazine1,1-dioxide
• 3,4-Dihydro-2H-1λ6,2,4-benzothiadiazine-1,1-dione

3,4-Dihydro-2H-benzo[E][1,2,4]thiadiazine 1,1-dioxide

CAS: 359-84-2

Phenoxybenzamine is a phenoxy compound with a benzoylamino group. It inhibits the activity of monoamine oxidase, which is an enzyme that catalyzes the oxidation of monoamines and the degradation of catecholamines. Phenoxybenzamine has been shown to be effective in vitro against nerve cells. This drug has also been shown to be effective in vivo by reducing diabetic neuropathy and sciatic nerve injury in rats. Phenoxybenzamine inhibits the activity of alkoxycarbonyl groups, which are found in polyfluoroalkyl substances such as perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS).

Formula: C₇H₈N₂O₂S

Purity: Min. 95%

Molecular weight: 184.22 g/mol

Ref: 3D-AAA35984