CAS 359436-56-9

(5S,7R,12S)-7,12-dihydroxy-17-(4-hydroxy-1-methyl-butyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

Description:

The chemical substance with the name "(5S,7R,12S)-7,12-dihydroxy-17-(4-hydroxy-1-methyl-butyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one" and CAS number "359436-56-9" is a complex organic compound characterized by its multi-ring structure, which is typical of steroid-like molecules. It features multiple hydroxyl (-OH) groups, indicating it has significant polar characteristics, which can influence its solubility and reactivity. The presence of the dimethyl and hydroxy groups suggests potential biological activity, possibly interacting with various biological pathways. The stereochemistry, indicated by the specific configuration at several chiral centers, is crucial for its biological function and interaction with receptors. This compound may be of interest in medicinal chemistry and pharmacology, particularly in the study of steroid hormones or related therapeutic agents. Its intricate structure and functional groups suggest potential applications in drug development or as a biochemical probe.

Formula: C₂₄H₄₀O₄

InChI: InChI=1/C24H40O4/c1-14(5-4-10-25)17-6-7-18-22-19(13-21(28)24(17,18)3)23(2)9-8-16(26)11-15(23)12-20(22)27/h14-15,17-22,25,27-28H,4-13H2,1-3H3/t14?,15-,17?,18?,19?,20-,21+,22?,23?,24?/m1/s1

3-Keto petromyzonol

CAS: 359436-56-9

3-Keto petromyzonol is a bile alocohol derivative that acts as a sex pheromone in Petromyzon marinus for drug design and biochemical experiments.

Formula: C₂₄H₄₀O₄

Color and Shape: Solid

Molecular weight: 392.57

Ref: TM-T40458

3-Keto Petromyzonol

Controlled Product

CAS: 359436-56-9

Applications Synthetic keto-derivative of Petromyzonol (P293500), a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). May be used to study the biochemical characteristics of these and other compounds containing the allocholic acid ring nucleus.
References Haslewood, G., et al.: Biochem. J., 114, 179 (1969); Sorensen, P.W., et al.: J. Gen. Physiol., 105, 569 (1995), Krasowski, M., et al.: Mol. Endocrinol., 19, 1720 (2005),

Formula: C₂₄H₄₀O₄

Color and Shape: Neat

Molecular weight: 392.57

Ref: TR-K200000

3-Keto petromyzonol

Controlled Product

CAS: 359436-56-9

3-Keto petromyzonol is a natural product that is biosynthesized in the liver from taurocholic acid. It has been shown to inhibit the synthesis of estradiol and progesterone in both rat and human tissue. 3-Keto petromyzonol has also been shown to have anti-obesity effects in mice, with decreased hepatic steatosis, as well as beneficial effects on insulin resistance and genes expression. The structural elucidation of 3-keto petromyzonol was accomplished by NMR spectroscopy, which revealed its disulfate structure. This chemical compound can be synthesized from methyl 2-(2′-chloroacetyl)malonate or from 1,4-dibromobutane. 3-Keto petromyzonol has been shown to inhibit ATP binding cassette transporter (ABC) proteins that are involved in cholesterol transport across the membrane. It may also act as a pheromone

Formula: C₂₄H₄₀O₄

Purity: Min. 95%

Molecular weight: 392.57 g/mol

Ref: 3D-FK24780