CAS 35960-33-9

asialoganglioside-gm2

Description:

Asialoganglioside GM2 is a glycosphingolipid, specifically a type of ganglioside that is characterized by the absence of sialic acid residues. It is primarily found in the membranes of certain cells, particularly in the nervous system. This compound plays a significant role in cell recognition, signaling, and interactions, particularly in neuronal tissues. Asialoganglioside GM2 is involved in various biological processes, including cell adhesion and modulation of immune responses. Its structure consists of a ceramide backbone linked to a carbohydrate moiety, which contributes to its functional properties. The absence of sialic acid makes it distinct from other gangliosides, influencing its biological activity and interactions with receptors. This substance is of interest in biomedical research, particularly in the context of neurobiology and potential therapeutic applications, including cancer immunotherapy, due to its role in tumor-associated antigens. Understanding its characteristics and functions can provide insights into cellular processes and disease mechanisms.

Synonyms:

• Ganglio-N-triaosylceramide
• Acetylgalactosaminyl-1-4-galactosyl-1-4-glucosyl-1-1-ceramide
• Asialo GM2
• G(A2) Ganglioside
• GA2 Ganglioside
• Galnac beta1-4Gal beta1-4Glc beta1-1Cer
• Gangliotriosylceramide
• Glycolipid G(A2)
• Ganglioside GA2

Ganglioside GM2 Asialo Mixture

CAS: 35960-33-9

Asialo-GM2: a glycosphingolipid lacking sialic acid, accumulates in Tay-Sachs/Sandhoff diseases, binds bacteria.

Formula: C₅₆H₁₀₄N₂O₁₈

Color and Shape: Solid

Molecular weight: 1093.444

Ref: TM-T38027

Gangliotriosyl Ceramide Gg3, asialo GM2

CAS: 35960-33-9

Formula: Unspecified

Purity: >98%

Color and Shape: Solid

Ref: 48-56-1110

GA2-Ganglioside

CAS: 35960-33-9

Formula: C₅₆H₁₀₄N₂O₁₈

Purity: ≥ 98%

Color and Shape: White to light-yellow solid or powder

Molecular weight: 1093.4

Ref: 7W-GC5605

GA2-Ganglioside

CAS: 35960-33-9

GA2-ganglioside is a ganglioside that is found in the membranes of cells. GA2-Ganglioside has been shown to inhibit the growth of tumors by binding to macrophages and T cells, which are two types of white blood cells. It has also been shown that GA2-Ganglioside can be used as a target for an antibody response against human HL-60 tumor cells. The antibody response induces cell lysis and reduces the size of the tumor. GA2-Ganglioside has also been shown to have anti-inflammatory properties, which may be due to its ability to bind to α subunits on bowel disease and infectious diseases, such as murine sarcoma virus, causing an antibody response that causes cell lysis and prevents replication of these viruses.

Formula: C₅₆H₁₀₄N₂O₁₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,093.43 g/mol

Ref: 3D-OG16402