CAS 3600-87-1

Desglymidodrine

Description:

Desglymidodrine, with the CAS number 3600-87-1, is a chemical compound that serves as a metabolite of the drug midodrine, which is primarily used to treat orthostatic hypotension. This substance is characterized by its structural modifications that differentiate it from its parent compound. Desglymidodrine is known to possess sympathomimetic properties, acting as an alpha-1 adrenergic agonist, which contributes to its ability to increase vascular tone and blood pressure. The compound is typically administered in a pharmaceutical context, and its pharmacological effects are closely related to its interaction with adrenergic receptors. In terms of physical properties, it is generally a white to off-white crystalline powder, soluble in water, and stable under standard conditions. Safety and handling precautions are essential, as with many pharmacologically active substances, to mitigate potential side effects or adverse reactions. Overall, Desglymidodrine plays a significant role in the management of certain cardiovascular conditions, reflecting its importance in therapeutic applications.

Formula: C₁₀H₁₅NO₃

InChI: InChI=1S/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3

InChI key: InChIKey=VFRCNXKYZVQYLX-UHFFFAOYSA-N

SMILES: C(CN)(O)C1=C(OC)C=CC(OC)=C1

Synonyms:

• 1-(2',5'-Dimethoxyphenyl)aminoethanol
• 1-(2,5-Dimethoxyphenyl)-2-aminoethanol
• 2-(2,5-Dimethoxyphenyl)-2-Hydroxyethanaminium Chloride
• 2-Amino-1-(2,5-Dimethoxyphenyl)Ethanol
• 2-Amino-1-(2,5-dimethoxyphenyl)ethan-1-ol
• Benzenemethanol, α-(aminomethyl)-2,5-dimethoxy-
• Benzyl alcohol, alpha-(aminomethyl)-2,5-dimethoxy-
• Benzyl alcohol, α-(aminomethyl)-2,5-dimethoxy-
• Deglymidodrine
• Desglymidodrine
• St 1059
• alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol

Midodrine Related Compound A (1-(2,5 Dimethoxyphenyl)-2-aminoethanol)

CAS: 3600-87-1

Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters, salts thereof, nesoi

Formula: C₁₀H₁₅NO₃

Color and Shape: White Off-White Light Yellow Powder

Molecular weight: 197.10519

Ref: 45-1443715

Midodrine USP Related Compound A (Desglymidodrine)

CAS: 3600-87-1

Formula: C₁₀H₁₅NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 197.23

Ref: 4Z-M-112

Midodrine USP Related Compound A-d6 (Desglymidodrine-d6)

CAS: 3600-87-1

Formula: C₁₀H₉D₆NO₃

Molecular weight: 203.27

Ref: 4Z-M-114

Desglymidodrine

CAS: 3600-87-1

Desglymidodrine (ST 1059) is an α1-adrenoceptor agonist and vasoconstrictor, used in cardiovascular research and neurocardiogenic syncope studies.

Formula: C₁₀H₁₅NO₃

Purity: 99.56%

Color and Shape: Solid

Molecular weight: 197.23

Ref: TM-T31388L

α-(Aminomethyl)-2,5-dimethoxybenzyl alcohol

CAS: 3600-87-1

α-(Aminomethyl)-2,5-dimethoxybenzyl alcohol

Formula: C₁₀H₁₅NO₃

Purity: 95%

Color and Shape: white solid

Molecular weight: 197.23g/mol

Ref: 54-OR18586

2-Amino-1-(2,5-dimethoxyphenyl)ethanol

Controlled Product

CAS: 3600-87-1

Formula: C₁₀H₁₅NO₃

Color and Shape: Neat

Molecular weight: 197.23

Ref: 86-MM3328.01

ST 1059(Desglymidodrine)

Controlled Product

CAS: 3600-87-1

Applications A metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects. Midodrine Related Compound A
References Zachariah, P.K., et al.: Clin. Pharm. & Thera., 39, 5, 586 (1986),

Formula: C₁₀H₁₅NO₃

Color and Shape: Neat

Molecular weight: 197.23

Ref: TR-S686650

ST 1059

Controlled Product

CAS: 3600-87-1

ST 1059 is a new antimicrobial peptide that is derived from fatty acid. It has been shown to have a matrix effect on blood pressure, as well as antimicrobial effects in the cardiovascular system. ST 1059 also has an oral prodrug form and can be administered orally. This drug may be used for the treatment of symptoms associated with high blood pressure, such as systolic pressure. Pharmacokinetic studies have been conducted in experimental models to determine the pharmacological treatment of ST 1059. The results showed that ST 1059 has a short half-life in rats and mice.
ST 1059 may also be used for the prevention of heart disease, by reducing cholesterol levels and fatty acids, as well as preventing plaque formation on artery walls.

Formula: C₁₀H₁₅NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 197.23 g/mol

Ref: 3D-FS27869