CAS 36016-38-3

tert-Butyl N-hydroxycarbamate

Description:

Tert-Butyl N-hydroxycarbamate is an organic compound characterized by its carbamate functional group, which features a tert-butyl group attached to a nitrogen atom that is also bonded to a hydroxy group. This compound is typically a white to off-white solid and is soluble in polar organic solvents. It is often used in organic synthesis, particularly as a protecting group for amines due to its stability under various reaction conditions. The presence of the hydroxy group enhances its reactivity, allowing for further transformations in synthetic pathways. Tert-Butyl N-hydroxycarbamate is also known for its role in the synthesis of various pharmaceuticals and agrochemicals. Safety data indicates that it should be handled with care, as with many organic compounds, due to potential irritant properties. Overall, its unique structure and reactivity make it a valuable intermediate in chemical synthesis.

Formula: C₅H₁₁NO₃

InChI: InChI=1S/C5H11NO3/c1-5(2,3)9-4(7)6-8/h8H,1-3H3,(H,6,7)

InChI key: InChIKey=DRDVJQOGFWAVLH-UHFFFAOYSA-N

SMILES: O(C(C)(C)C)C(NO)=O

Synonyms:

• 1,1-Dimethylethyl N-hydroxycarbamate
• Benzotriazol-1-YL 9-Fluorenylmethyl Carbonate
• Carbamic acid, N-hydroxy-, 1,1-dimethylethyl ester
• Carbamic acid, hydroxy-, 1,1-dimethylethyl ester
• Carbamic acid, hydroxy-, tert-butyl ester
• Hydroxycarbamic acid 1,1-dimethylethyl ester
• N-(tert-Butoxycarbonyl)hydroxylamine
• N-(tert-Butyloxycarbonyl)hydroxylamine
• N-Boc-hydroxyamine
• N-Hydroxycarbamic acid tert-butyl ester
• N-t-Butyloxycarbonyl hydroxylamine
• NSC 131086
• NSC 144620
• Tert-Butyl Hydroxycarbamate
• t-Butyl N-hydroxycarbomate
• tert-Butoxycarbonylhydroxylamine
• tert-Butoxyhydroxamic acid
• tert-Butyl N-hydroxycarbamate

tert-Butyl N-Hydroxycarbamate

CAS: 36016-38-3

Formula: C₅H₁₁NO₃

Purity: >97.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 133.15

Ref: 3B-H0848

tert-Butyl N-Hydroxycarbamate

CAS: 36016-38-3

Formula: C₅H₁₁NO₃

Purity: 96%

Color and Shape: Chunks,Crystalline Powder

Molecular weight: 133.147

Ref: 10-F044878

N-tert-Butoxycarbonylhydroxylamine

CAS: 36016-38-3

Formula: C₅H₁₁NO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 133.1457

Ref: IN-DA0035ND

tert-Butyl-n-hydroxycarbamate

CAS: 36016-38-3

tert-Butyl-n-hydroxycarbamate

Formula: C₅H₁₁NO₃

Purity: 98%

Color and Shape: white solid

Molecular weight: 133.15g/mol

Ref: 54-OR322101

N-Boc-hydroxylamine

CAS: 36016-38-3

N-Boc-hydroxylamine is an efficient method for the preparation of epoxides from carboxylic acids. The reaction system is a ruthenium complex in trifluoroacetic acid with an effective reaction time of 20 minutes and a stereoselective transfer mechanism. The carbamic acid group on the amine reacts with the epoxide to form a hydroxamic ester. Preparation of N-Boc-hydroxylamine can be accomplished by reacting hydroxylamine with a boc-protected alcohol, which then undergoes decarboxylation.

Formula: C₅H₁₁NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 133.15 g/mol

Ref: 3D-FB36017

N-Boc-hydroxylamine

Controlled Product

CAS: 36016-38-3

Applications N-Boc-hydroxylamine is the protected form of Hydroxylamine (HCl: H943705). Hydroxylamine is used as an inhibitor between Z and P680 in photosystem II within plant chloroplasts. Hydroxylamine is also known to induce chromosomal damage in mammalian cells, inducing mutagenesis.
References Ghanotakis, D. & Babcock, G.: FEBS Lett., 153, 231 (1983); Somers, C. & Hsu, T.: P. Natl. Acad. Sci. USA, 48, 937 (1962)

Formula: C₅H₁₁NO₃

Color and Shape: Neat

Molecular weight: 133.15

Ref: TR-B656470

N-Boc-hydroxylamine, 98+%

CAS: 36016-38-3

N-Boc-hydroxylamine is used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts. It acts as a reagent for the synthesis of hydroxylamine derivatives t-butyl-N-(acyloxy)carbamates and N,O-diacylated N-hydroxyarylsulfonamides. This Thermo Scientific Chemicals br

Formula: C₅H₁₁NO₃

Purity: 98+%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 133.15

Ref: 02-A10349