CAS 36062-05-2

Hexahydrocurcumin

Description:

Hexahydrocurcumin is a chemical compound derived from curcumin, the active component of turmeric. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents but has limited solubility in water. Hexahydrocurcumin is known for its antioxidant properties and potential health benefits, including anti-inflammatory and anticancer effects. The compound is formed through the hydrogenation of curcumin, which alters its chemical structure and enhances its stability. Its molecular formula reflects the saturation of the original curcumin structure, leading to differences in reactivity and biological activity. Hexahydrocurcumin has garnered interest in various fields, including pharmaceuticals and nutraceuticals, due to its potential therapeutic applications. Additionally, it is being studied for its role in enhancing the bioavailability of curcumin and its derivatives. As research continues, the full spectrum of its properties and applications is being explored, making it a compound of significant interest in both scientific and health-related contexts.

Formula: C₂₁H₂₆O₆

InChI: InChI=1/C21H26O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16,22,24-25H,3-4,7-8,13H2,1-2H3

InChI key: InChIKey=RSAHICAPUYTWHW-UHFFFAOYSA-N

SMILES: C(CC(CC(CCC1=CC(OC)=C(O)C=C1)=O)O)C2=CC(OC)=C(O)C=C2

Synonyms:

• 3-Heptanone, 5-Hydroxy-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)-
• 5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone
• Hexahydrocurcumin
• 5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one
• 1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one
• Hexahydrocurcumin, BR
• (RS)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone
• 1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone
• 5-Hydroxy-1-(4-hydroxy-3-Methoxycyclohexyl)-7-(4-hydroxy-3-Methoxyphenyl)heptan-3-one

Hexahydrocurcumin

CAS: 36062-05-2

Formula: C₂₁H₂₆O₆

Molecular weight: 374.43

Ref: 7W-GL2328

Hexahydrocurcumin

CAS: 36062-05-2

Hexahydrocurcumin

Purity: ≥98%

Molecular weight: 374.43g/mol

Ref: 54-BUP08862

Hexahydrocurcumin

CAS: 36062-05-2

Formula: C₂₁H₂₆O₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 374.433

Ref: BP-SBP02527

Hexahydro Curcumin

CAS: 36062-05-2

Formula: C₂₁H₂₆O₆

Molecular weight: 374.43

Ref: 4Z-C-6922

Hexahydrocurcumin

CAS: 36062-05-2

Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.

Formula: C₂₁H₂₆O₆

Purity: 99.43% - 99.88%

Color and Shape: Solid

Molecular weight: 374.43

Ref: TM-TQ0288

Hexahydrocurcumin

CAS: 36062-05-2

Ketone phenol

Formula: C₂₁H₂₆O₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 374.43

Ref: 5G-82559

Hexahydrocurcumin-d6

Controlled Product

CAS: 36062-05-2

Applications Hexahydrocurcumin-d6 is an isotope labelled degradation product of Curcumin (C838500), a dietary anti-inflammatory and chemopreventive agent consisting of two methoxyphenol rings connected by a conjugated heptadienedione chain.
References Gordon, D.N., et al.: J. Biol. Chem., 290, 4817 (2015);

Formula: C₂₁H₂₀D₆O₆

Color and Shape: Neat

Molecular weight: 380.46

Ref: TR-H281277

Hexahydrocurcumin

CAS: 36062-05-2

Hexahydrocurcumin is a hydrogenated derivative of curcumin, which is a natural compound derived from the rhizome of the turmeric plant (Curcuma longa). This derivative is obtained through the catalytic hydrogenation of curcumin, resulting in enhanced chemical stability and bioavailability compared to the parent compound. Hexahydrocurcumin works by effectively scavenging free radicals and exhibiting robust antioxidant properties, which are superior to those of curcumin itself. This enhancement is attributed to the saturation of the double bonds in the structure, which reduces its susceptibility to degradation.

Formula: C₂₁H₂₆O₆

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 374.43 g/mol

Ref: 3D-XH178625

Hexahydrocurcumin

Controlled Product

CAS: 36062-05-2

Applications Hexahydrocurcumin is a reagent in the synthesis of Gingerenone A (G387500) which is an antifungal and antiparasitic diarylheptenone that is isolated from Zingiber officinale (more commonly known as ginger), a medicinal plant that is used to treat inflammation and musculoskeletal disorders.
References Ali, B., et al.: Food Chem. Toxicol., 46, 409 (2008); Bordia, A., et al.: Prost. Leuk. Ess. Fat. Acids, 56, 379 (1997); Choi, W., et al.: J. Appl. Biomed., 11, 15 (2013); Riaz, T., et al.: Nat. Prod. Res., 24, 1131 (2010); Srivastava, K. & Mustava, T.: Med. Hypoth., 39, 342 (1992)

Formula: C₂₁H₂₆O₆

Color and Shape: Light Yellow

Molecular weight: 374.43

Ref: TR-H281370

HEXAHYDROCURCUMIN

CAS: 36062-05-2

Formula: C₂₁H₂₆O₆

Color and Shape: Solid

Molecular weight: 374.4275

Ref: IN-DA00C6J4