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CAS 360760-58-3

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EG31

Description:
EG31, identified by its CAS number 360760-58-3, is a chemical compound that belongs to the category of glycol ethers. It is characterized by its low volatility, good solubility in water and organic solvents, and relatively low toxicity compared to other solvents. EG31 is often utilized in various industrial applications, including as a solvent in coatings, inks, and cleaning products due to its effective solvating properties. The compound typically exhibits a moderate boiling point and a low flash point, which necessitates careful handling and storage to prevent fire hazards. Additionally, EG31 is known for its ability to enhance the performance of formulations by improving flow and leveling properties. Its environmental impact is generally considered to be lower than that of more volatile organic compounds, making it a preferred choice in formulations aimed at reducing emissions. As with any chemical, proper safety measures should be observed when handling EG31 to mitigate any potential health risks.
Formula:C30H13Br2N3O6
Synonyms:
  • 1H-Isoindole-1,3(2H)-dione, 2-[3,5-bis(6-bromo-4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-
  • EG31
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  • EG31

    CAS:
    EG31 is an EGFR inhibitor that effectively suppresses the proliferation of triple-negative breast cancer (TNBC) cells by inhibiting the EGFR signaling pathway. It demonstrates a GI50 value of 498.90 nM for MDA-MB-231 cells and 740.73 nM for Hs578T cells, while also inducing apoptosis. Additionally, EG31 retains its antiproliferative activity against 5-fluorouracil (5-FU) resistant TNBC cells, with a GI50 of 519.5 nM. EG31 is applicable in research on TNBC resistance.
    Formula:C30H13Br2N3O6
    Color and Shape:Solid
    Molecular weight:671.25