CAS 36077-41-5

Leucylisoleucine

Description:

Leucylisoleucine, with the CAS number 36077-41-5, is a dipeptide composed of the amino acids leucine and isoleucine. It is classified as a non-polar, hydrophobic compound due to the presence of branched-chain amino acids, which contribute to its structural stability and solubility characteristics. This dipeptide is typically found in various biological systems and can play a role in protein synthesis and metabolism. Leucylisoleucine may exhibit specific biological activities, including potential effects on muscle protein synthesis and energy metabolism, making it of interest in nutritional and pharmaceutical research. Its molecular structure features a peptide bond linking the two amino acids, and it can exist in various forms depending on the pH and environmental conditions. As with many peptides, its properties can be influenced by factors such as temperature and solvent conditions, which can affect its stability and reactivity. Overall, leucylisoleucine serves as a valuable model for studying peptide interactions and functions in biological systems.

Formula: C₁₂H₂₄N₂O₃

InChI: InChI=1S/C12H24N2O3/c1-5-8(4)10(12(16)17)14-11(15)9(13)6-7(2)3/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t8-,9-,10-/m0/s1

InChI key: InChIKey=AZLASBBHHSLQDB-GUBZILKMSA-N

SMILES: [C@H](NC([C@H](CC(C)C)N)=O)([C@H](CC)C)C(O)=O

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Isoleucine, <smallcap>L</span>-leucyl-
• <span class="text-smallcaps">L</smallcap>-Isoleucine, N-<smallcap>L</span>-leucyl-
• <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-isoleucine
• L-Isoleucine,N-L-leucyl-
• L-Leucyl-L-isoleucine
• Leucylisoleucine
• 165: PN: WO2011146121 PAGE: 117 claimed sequence
• L-Isoleucine, L-leucyl-

H-Leu-Ile-OH

CAS: 36077-41-5

According to Nitta et al. H-Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis. Alkam et al. observed that dietary supplementation with the hydrophobic dipeptide prevents the impairment of memory induced by amyloid β in mice via restraining the hyperphosphorylation of extracellular signal-regulated kinase. Leu-Ile forms nanotubes in the presence of D-leucine.

Formula: C₁₂H₂₄N₂O₃

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 244.33

Ref: 01-4002987

H-Leu-Ile-OH

CAS: 36077-41-5

Formula: C₁₂H₂₄N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 244.3306

Ref: IN-DA00C7RR

L-Leucyl-L-isoleucine

CAS: 36077-41-5

L-Leucyl-L-isoleucine

Purity: 95%

Molecular weight: 244.33g/mol

Ref: 54-OR1072676

Leucylisoleucine

Controlled Product

CAS: 36077-41-5

Applications (2S,3S)-2-((S)-2-Amino-4-methylpentanamido)-3-methylpentanoic acid (cas# 36077-41-5) is a useful research chemical.

Formula: C₁₂H₂₄N₂O₃

Color and Shape: Neat

Molecular weight: 244.33

Ref: TR-A899030

H-Leu-Ile-OH

CAS: 36077-41-5

Leucine-enkephalin is a type of protein that has neurotrophic effects and is produced by the kidney bean. It is a member of the opioid peptide family, which is a class of molecules that are important in modulating several biological processes. Leucine-enkephalin has been shown to have neuroprotective properties, which may be due to its ability to inhibit neuronal death. This protein also stimulates uptake of glucose into cells and immunosuppressant effects. Leucine-enkephalin has been shown to inhibit cell growth in culture and has neurotrophic effects in wild-type mice.

Formula: C₁₂H₂₄N₂O₃

Purity: Min. 95%

Molecular weight: 244.33 g/mol

Ref: 3D-FL108091