CAS 36082-50-5

5-Bromo-2,4-dichloropyrimidine

Description:

5-Bromo-2,4-dichloropyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with bromine and chlorine atoms. Its molecular structure features a six-membered ring containing two nitrogen atoms at positions 1 and 3, with bromine at position 5 and chlorine atoms at positions 2 and 4. This compound is typically a solid at room temperature and is known for its role in various chemical syntheses, particularly in the pharmaceutical industry, where it can serve as an intermediate in the production of biologically active compounds. It exhibits moderate solubility in organic solvents and is relatively stable under standard conditions. The presence of halogen substituents contributes to its reactivity, making it useful in nucleophilic substitution reactions. Additionally, 5-Bromo-2,4-dichloropyrimidine may exhibit biological activity, which has been the subject of research in medicinal chemistry. Proper handling and safety precautions are essential due to its potential toxicity and environmental impact.

Formula: C₄HBrCl₂N₂

InChI: InChI=1/C4HBrCl2N2/c5-2-1-8-4(7)9-3(2)6/h1H

InChI key: InChIKey=SIKXIUWKPGWBBF-UHFFFAOYSA-N

SMILES: ClC=1C(Br)=CN=C(Cl)N1

Synonyms:

• 2,4-Dichloro-5-bromo pyrimidine
• 2,4-Dichloro-5-bromopyrimidine
• 2,6-Dichloro-5-bromopyrimidine
• 5-Bromo-2,4-Dichloropyridimidine
• 5-Bromo-2,6-dichloropyrimidine
• Buttpark 48\06-22
• NSC 152517
• Pyrimidine, 5-bromo-2,4-dichloro-
• Timtec-Bb Sbb003301
• 5-Bromo-2,4-dichloropyrimidine
• 5-Bromo-2,4-dichloropyrimidine
• 5-BROMO-2,4-DICHLOROPYRIMIDINE 99%

5-Bromo-2,4-dichloropyrimidine, 98%

CAS: 36082-50-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄HBrCl₂N₂

Purity: 98%

Color and Shape: Clear colorless, Liquid

Molecular weight: 227.87

Ref: 02-B25365

5-Bromo-2,4-dichloropyrimidine

CAS: 36082-50-5

Formula: C₄HBrCl₂N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 227.8741

Ref: IN-DA00347C

5-Bromo-2,4-dichloropyrimidine

CAS: 36082-50-5

Formula: C₄HBrCl₂N₂

Purity: ≥ 98.0%

Color and Shape: White to light brown solid or colourless to light yellow liquid

Molecular weight: 227.88

Ref: 7W-GK3915

5-Bromo-2,4-dichloropyrimidine

CAS: 36082-50-5

5-Bromo-2,4-dichloropyrimidine

Formula: C₄HBrCl₂N₂

Purity: 99%

Color and Shape: white low melting solid

Molecular weight: 227.87414g/mol

Ref: 54-OR9965

5-Bromo-2,4-dichloropyrimidine

CAS: 36082-50-5

Formula: C₄HBrCl₂N₂

Purity: >97.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 227.87

Ref: 3B-B2823

5-Bromo-2,4-dichloro-pyrimidine

CAS: 36082-50-5

Formula: C₄HBrCl₂N₂

Purity: 97%

Color and Shape: Low Melting Solid

Molecular weight: 227.87

Ref: 10-F011581

5-Bromo-2,4-dichloropyrimidine

CAS: 36082-50-5

5-Bromo-2,4-dichloropyrimidine is an aryl halide compound that is synthesized from 2,4-dichloropyrimidine and bromine. It has been shown to have inhibitory activities against cancer cells in vitro. 5-Bromo-2,4-dichloropyrimidine is used in the synthesis of the drug palbociclib (also known as PLX4720), which prevents mitotic progression by binding to the mitotic checkpoint protein (e.g., cyclin B). The reaction yield for this compound is low and its absorption enhancer properties are not well understood. 5-Bromo-2,4-dichloropyrimidine has also been used in conjunction with crotonic acid as a potential anticancer agent.

Formula: C₄HBrCl₂N₂

Purity: Min. 95%

Color and Shape: Off-White Clear Liquid

Molecular weight: 227.87 g/mol

Ref: 3D-FB10261

2,4-Dichloro-5-bromopyrimidine

Controlled Product

CAS: 36082-50-5

Applications 2,4-Dichloro-5-bromopyrimidine (cas# 36082-50-5) is a compound useful in organic synthesis.

Formula: C₄HBrCl₂N₂

Color and Shape: Neat

Molecular weight: 227.87

Ref: TR-D433775

Ribociclib Impurity 30

CAS: 36082-50-5

Formula: C₄HBrCl₂N₂

Molecular weight: 227.87

Ref: ST-EA-CP-R48019