CAS 36130-02-6

Pregna-1,4-diene-3,20-dione, 6-fluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,16α)-

Description:

Pregna-1,4-diene-3,20-dione, 6-fluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,16α)-, commonly referred to by its CAS number 36130-02-6, is a synthetic steroid compound. This substance exhibits characteristics typical of corticosteroids, including anti-inflammatory and immunosuppressive properties. The presence of a fluorine atom at the 6-position enhances its potency and metabolic stability. The hydroxy group at the 11-position contributes to its biological activity, while the 16-methyl group may influence its receptor binding affinity and pharmacokinetics. The compound's structure includes a dione functional group, which is crucial for its interaction with biological systems. Its unique side chain, characterized by a pentyl group, may affect its solubility and distribution in biological tissues. Overall, this compound is of interest in pharmacology and medicinal chemistry, particularly for its potential therapeutic applications in treating various inflammatory and autoimmune conditions. However, detailed studies on its pharmacodynamics and pharmacokinetics are essential for understanding its full therapeutic potential and safety profile.

Formula: C₂₇H₃₇FO₅

InChI: InChI=1S/C27H37FO5/c1-5-6-7-23(32)33-14-22(31)24-15(2)10-18-17-12-20(28)19-11-16(29)8-9-26(19,3)25(17)21(30)13-27(18,24)4/h8-9,11,15,17-18,20-21,24-25,30H,5-7,10,12-14H2,1-4H3/t15-,17+,18+,20+,21+,24-,25-,26+,27+/m1/s1

InChI key: InChIKey=ASVQNGFDDHFBPT-VJBCMVKLSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(C[C@@H](C)[C@@H]2C(COC(CCCC)=O)=O)[H]

Synonyms:

• Pregna-1,4-diene-3,20-dione, 6-fluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,16α)-
• 6α-Fluoro-11β-hydroxy-21-valeryloxy-16α-methylpregna-1,4-diene-3,20-dione

Fluocortolone Impurity 1

CAS: 36130-02-6

Formula: C₂₇H₃₇FO₅

Color and Shape: White To Off-White Solid

Molecular weight: 460.59

Ref: 4Z-F-071015

6α-Fluoro-11β-hydroxy-21-valeryloxy-16α-Methylpregna-1,4-diene-3,20dione

Controlled Product

CAS: 36130-02-6

Formula: C₂₇H₃₇FO₅

Color and Shape: Neat

Molecular weight: 460.578

Ref: TR-F839270

Fluocortolone Impurity 1

Controlled Product

CAS: 36130-02-6

Fluocortolone Impurity 1 is a metabolite of fluocortolone. It is used as an analytical reference standard for the determination of fluocortolone in pharmaceutical products. Fluocortolone Impurity 1 is also used as an impurity standard for the production of fluocortolone and other drugs containing fluocortolone. Fluocortolone Impurity 1 is listed in the U.S. Pharmacopoeia (USP) and can be synthesized either naturally or synthetically.

Formula: C₂₇H₃₇FO₅

Purity: Min. 95%

Molecular weight: 460.59 g/mol

Ref: 3D-IF180650

Diflucortolone Valerate Impurity 10

CAS: 36130-02-6

Formula: C₂₇H₃₇FO₅

Molecular weight: 460.59

Ref: ST-EA-CP-D115009