CAS 3614-30-0

emepronium bromide

Description:

Emepronium bromide is a quaternary ammonium compound primarily used as a muscle relaxant and antispasmodic agent. It is characterized by its ability to block the action of acetylcholine at the neuromuscular junction, leading to muscle relaxation. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a moderate stability profile. Emepronium bromide has a relatively low toxicity, making it suitable for therapeutic applications, although it may cause side effects such as dry mouth, blurred vision, and urinary retention due to its anticholinergic properties. Its pharmacological effects are primarily attributed to its interaction with muscarinic receptors, influencing smooth muscle contraction. The compound is often administered in clinical settings for conditions involving muscle spasms or gastrointestinal disorders. As with any medication, proper dosage and monitoring are essential to minimize potential adverse effects and ensure efficacy.

Formula: C₂₀H₂₈BrN

InChI: InChI=1/C20H28N.BrH/c1-5-21(3,4)17(2)16-20(18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17,20H,5,16H2,1-4H3;1H/q+1;/p-1

InChI key: InChIKey=UVKFSMBPRQBNCH-UHFFFAOYSA-M

SMILES: C(CC([N+](CC)(C)C)C)(C1=CC=CC=C1)C2=CC=CC=C2.[Br-]

Synonyms:

• (1-Methyl-3,3-diphenylpropyl)dimethylethylammonium bromide
• Ammonium, ethyldimethyl(1-methyl-3,3-diphenylpropyl)-, bromide
• Benzenepropanaminium, N-ethyl-N,N,alpha-trimethyl-gamma-phenyl-, bromide (9CI)
• Benzenepropanaminium, N-ethyl-N,N,α-trimethyl-γ-phenyl-, bromide
• Benzenepropanaminium, N-ethyl-N,N,α-trimethyl-γ-phenyl-, bromide (1:1)
• Bromure d'emepronium
• Bromure d'emepronium [INN-French]
• Bromuro de emepronio
• Bromuro de emepronio [INN-Spanish]
• Cetiprin
• Dimethylethyl(beta-benzhydrylisopropyl)ammonium bromide
• Dimethylethyl(β-benzhydrylisopropyl)-ammonium bromide
• Emepron bromide
• Emeprone
• Emeprone bromide
• Emepronii bromidum
• Emepronii bromidum [INN-Latin]
• Emepronium bromide [INN:BAN]
• Emeproniumbromid
• Emeproniumbromid [German]
• Ethyl(3,3-diphenyl-1-methylpropyl)dimethylammonium bromide
• Ethyldimethyl(1-methyl-3,3-diphenylpropyl)ammonium bromide
• Hexanium
• N-ethyl-N,N-dimethyl-4,4-diphenylbutan-2-aminium
• N-ethyl-N,N-dimethyl-4,4-diphenylbutan-2-aminium bromide
• Restenacht
• Ripirin
• Uro-Ripirin
• Emepronium bromide
• Detrulisin
• N-Ethyl-N,N,α-triMethyl-γ-phenylbenzenepropanaMiniuM BroMide

Emepronium Bromide

Controlled Product

CAS: 3614-30-0

Applications Antispasmodic. Used in treatment of urinary incontinence. Anticholinergic overactive bladder.
References Hennessey, A., et al.: J. Neurol., 246, 1027 (1999), Brown, J., et al.: Obstet. Gynecol., 94, 66 (1999), Milsom, I., et al.: Br. J. Urol. Int., 87, 760 (2001),

Formula: C₂₀H₂₈N·Br

Color and Shape: Neat

Molecular weight: 362.35

Ref: TR-E521500

Emepronium bromide

CAS: 3614-30-0

Emepronium bromide is an anticholinergic agent that has been shown to be effective in the treatment of overactive bladder. It is used for the relief of symptoms in women with overactive bladder, including urinary frequency, urgency, and urge incontinence. Emepronium bromide is a prodrug that is hydrolyzed by esterases to form emepronium. The prodrug form binds to acetylcholine receptors in the bladder and detrusor muscle, which prevents acetylcholine from binding to these receptors and activating them. This prevents bladder contractions and reduces the symptoms associated with overactive bladder.

Formula: C₂₀H₂₈BrN

Purity: Min. 95%

Molecular weight: 362.35 g/mol

Ref: 3D-FE22662

Emepronium-d5 Bromide

Controlled Product

CAS: 3614-30-0

Applications Labelled Emepronium Bromide (E521500). Antispasmodic. Used in treatment of urinary incontinence. Anticholinergic overactive bladder.
References Hennessey, A., et al.: J. Neurol., 246, 1027 (1999), Brown, J., et al.: Obstet. Gynecol., 94, 66 (1999), Milsom, I., et al.: Br. J. Urol. Int., 87, 760 (2001),

Formula: C₂₀D₅H₂₃N·Br

Color and Shape: Neat

Molecular weight: 367.378

Ref: TR-E521502

Emepronium bromide

CAS: 3614-30-0

Emepronium bromide: antispasmodic anticholinergic for urinary issues; risks esophageal ulceration; take upright with water; poorly absorbed; doesn't enter CNS.

Formula: C₂₀H₂₈BrN

Color and Shape: Solid

Molecular weight: 362.35

Ref: TM-T69363

Emepronium Bromide

CAS: 3614-30-0

Color and Shape: Neat

Ref: 61-FOR3064.00