CAS 3616-42-0

D-Glucosamine 6-phosphate

Description:

D-Glucosamine 6-phosphate is an amino sugar derivative of glucose, characterized by the presence of an amino group and a phosphate group attached to the sixth carbon of the glucose molecule. It plays a crucial role in various biological processes, particularly in the synthesis of glycosaminoglycans and glycoproteins, which are essential components of the extracellular matrix and connective tissues. This compound is involved in metabolic pathways, including the hexosamine biosynthetic pathway, which contributes to the regulation of cellular signaling and energy metabolism. D-Glucosamine 6-phosphate is typically found in its phosphate form, which enhances its solubility in aqueous solutions. It is also known for its potential therapeutic applications, particularly in the treatment of osteoarthritis and joint health, due to its role in cartilage formation and repair. The compound is generally stable under physiological conditions but may be sensitive to extreme pH levels and high temperatures. Its molecular structure and properties make it an important subject of study in biochemistry and pharmacology.

Formula: C₆H₁₄NO₈P

InChI: InChI=1S/C6H14NO8P/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,9-11H,2,7H2,(H2,12,13,14)/t3-,4+,5+,6+/m0/s1

InChI key: InChIKey=AEJSSXDYDSUOOZ-SLPGGIOYSA-N

SMILES: [C@H]([C@@H]([C@H](C=O)N)O)([C@@H](COP(=O)(O)O)O)O

Synonyms:

• 2-Amino-2-deoxy-<span class="text-smallcaps">D</span>-glucose 6-phosphate
• 2-Amino-2-deoxyglucose 6-phosphate
• 2-Amino-<span class="text-smallcaps">D</span>-glucose-6-phosphate
• 2-amino-2-deoxy-6-O-phosphono-D-glucose
• 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose
• 2-amino-2-deoxy-6-O-phosphonohexopyranose
• 2-amino-2-deoxy-6-O-phosphonohexose
• <span class="text-smallcaps">D</span>-Glucosamine 6-phosphate
• <span class="text-smallcaps">D</span>-Glucose, 2-amino-2-deoxy-, 6-(dihydrogen phosphate)
• D-Glucosamine-6-phosphate
• D-Glucose, 2-amino-2-deoxy-, 6-(dihydrogen phosphate)
• Glucosamine 6-phosphate

2-Amino-2-deoxy-D-glucose 6-phosphate

CAS: 3616-42-0

Formula: C₆H₁₄NO₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 259.1510

Ref: IN-DA007B7Z

D-Glucosamine 6-phosphate

CAS: 3616-42-0

D-Glucosamine 6-phosphate (D-GlcN-6-P) is an endogenous metabolite, inhibiting nitric oxide synthesis in endothelial cells, suitable for diabetes research.

Formula: C₆H₁₄NO₈P

Purity: 99.76%

Color and Shape: Solid

Molecular weight: 259.15

Ref: TM-T78485

D-Glucosamine 6-phosphate

CAS: 3616-42-0

Formula: C₆H₁₄NO₈P

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 259.15

Ref: 7W-GC8013

D-Glucosamine 6-phosphate

CAS: 3616-42-0

D-Glucosamine 6-phosphate

Purity: 98%

Molecular weight: 259.15g/mol

Ref: 54-OR1035827

D-Glucosamine 6-Phosphate Hydrate

CAS: 3616-42-0

Applications Galactosamine-6-phosphate was identified as a component of the coat of the Bacillus megaterium QM B1551 spore. It was one of the main constituents of the outermost layer of the spore coat, but it was absent from the other integuments including the cortex. These findings suggest that galactosamine-6-phosphate comprises the phosphorus-containing skeleton structure of the spore coat.
References Dabich, D., et al.: J. Biol. Chem., 241, 415 (1966), Nasu M., et al.: Microb. Immunol., 28, 181 (1984),

Formula: C₆H₁₆NO₉P

Color and Shape: White To Off-White

Molecular weight: 277.17

Ref: TR-G515050

D-Glucosamine-13C6 6-Phosphate Hydrate

Controlled Product

CAS: 3616-42-0

Formula: C₆H₁₅NO₈P·(H₂O)

Color and Shape: Neat

Molecular weight: 278.06409

Ref: TR-G515052

D-Glucosamine 6-phosphate

CAS: 3616-42-0

D-Glucosamine 6-phosphate is a non-essential amino acid that belongs to the group of nucleotide sugar phosphates. It is a metabolite of the sugar D-glucose and it plays an important role in the energy metabolism of bacteria, plants, and animals. It has been shown to have anti-cancer effects on prostate cancer cells. D-Glucosamine 6-phosphate inhibits methyltransferase activity by binding to the enzyme's active site. This inhibition prevents DNA synthesis, leading to cell death. The structural analysis has been done using NMR spectroscopy on d-arabinose as a model substrate.

Formula: C₆H₁₄NO₈P

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 259.15 g/mol

Ref: 3D-MG09772