CAS 362-05-0

2-Hydroxyestradiol

Description:

2-Hydroxyestradiol is a naturally occurring estrogen and a metabolite of estradiol, which plays a significant role in the regulation of various physiological processes in the body. It is characterized by its hydroxyl group (-OH) positioned at the second carbon of the estradiol structure, which influences its biological activity and potency. This compound exhibits estrogenic activity, contributing to the development and maintenance of female reproductive tissues, as well as influencing bone density and cardiovascular health. 2-Hydroxyestradiol is also involved in the metabolism of estradiol, serving as a marker for estrogen metabolism in various biological studies. Its chemical formula is C18H24O3, and it has a molecular weight that reflects its structure. The compound is typically found in biological fluids and tissues, and its levels can be indicative of hormonal balance or imbalances. Due to its role in estrogen metabolism, 2-hydroxyestradiol has been studied for its potential implications in hormone-related conditions and diseases, including breast cancer and cardiovascular disorders.

Formula: C₁₈H₂₄O₃

InChI: InChI=1/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1

InChI key: InChIKey=DILDHNKDVHLEQB-XSSYPUMDSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=C(O)C4)(CC1)[H])[H])(CC[C@@H]2O)[H]

Synonyms:

• (17Beta)-Estra-1(10),2,4-Triene-2,3,17-Triol
• (17beta)-Estra-1,3,5(10)-triene-2,3,17-triol
• (17β)-Estra-1,3,5(10)-triene-2,3,17-triol
• 2,3,17β-Trihydroxyestra-1,3,5(10)-triene
• 2-OH-Estradiol
• 2-Oh-E2
• Brn 2219367
• Ccris 8709
• Estra-1(10),2,4-Triene-2,3,17-Triol
• Estra-1,3,5(10)-triene-2,3,17-beta-triol
• Estra-1,3,5(10)-triene-2,3,17-triol, (17β)-
• Estra-1,3,5(10)-triene-2,3,17β-triol
• Nsc 61711
• 2-Hydroxyestradiol
• 4-06-00-07547 (Beilstein Handbook Reference)
• 2-OH-E2α
• 2-Hydroxy-17b-estradiol
• C05301
• 1,3,5(10)-estratriene-2,3-17β-triol
• Estra-1,3,5(10)-triene-2,3,17-triol
• 2-Hydroxyestradiol-17α
• Estra-1(10),2,4-triene-2,3,17β-triol
• 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL
• 2,3,17-Trihydroxyestra-1,3,5(10)-triene
• 2-HYDROXY 17-BETA-ESTRADIOL
• 2-Hydroxy-17-estradiol
• 2-Hydroxy-17β-estradiol
• (17β)-2-Hydroxyestradiol
• 2-Hydroxyestradiol-17beta
• 2,3,17BETA-TRIHYDROXY-1,3,5[10]-ESTRATRIENE
• 1,3,5[10]-ESTRATRIENE-2,3-17BETA-TRIOL
• (17)-Estra-1,3,5(10)-triene-2,3,17-triol

2-Hydroxyestradiol

CAS: 362-05-0

Formula: C₁₈H₂₄O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 288.3814

Ref: IN-DA00C0VZ

2-Hydroxyestradiol

CAS: 362-05-0

Formula: C₁₈H₂₄O₃

Molecular weight: 288.38

Ref: 7W-GL9120

2-Hydroxy-17-β-estradiol 100 µg/mL in Acetonitrile

CAS: 362-05-0

Formula: C₁₈H₂₄O₃

Color and Shape: Single Solution

Molecular weight: 288.38

Ref: 04-A14231505AL-100

2-Hydroxy-17β-estradiol

CAS: 362-05-0

Applications A metabolite of Estradiol.
References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),

Formula: C₁₈H₂₄O₃

Color and Shape: Light Yellow To Dark Yellow

Molecular weight: 288.38

Ref: TR-H941890

2-Hydroxy-17b-estradiol

Controlled Product

CAS: 362-05-0

17β-Estradiol is a hormone that is synthesized from estradiol benzoate. It is found in the ovaries and testes, as well as in other tissues. 17β-Estradiol has physiological effects such as increasing growth of sex organs, stimulating breast development, and regulating the menstrual cycle. This compound can also be detected in human serum. The 2-hydroxy form of 17β-estradiol can be used to measure the concentration of this hormone through electrochemical detection using a model system.

Formula: C₁₈H₂₄O₃

Purity: Min. 95%

Molecular weight: 288.38 g/mol

Ref: 3D-FH24182

2-Hydroxyestradiol

CAS: 362-05-0

Formula: C₁₈H₂₄O₃

Molecular weight: 288.39

Ref: ST-EA-CP-E28043