CAS 362-07-2: 2-Methoxyestradiol
Description:2-Methoxyestradiol (CAS 362-07-2) is a naturally occurring estrogen metabolite derived from estradiol. It is characterized by its methoxy group at the C2 position of the estradiol structure, which influences its biological activity. This compound exhibits a range of pharmacological properties, including anti-angiogenic, anti-inflammatory, and potential anti-cancer effects. It has been studied for its role in inhibiting the proliferation of various cancer cell types and promoting apoptosis. Additionally, 2-Methoxyestradiol has been shown to modulate vascular function and may have implications in cardiovascular health. The substance is typically found in a solid state at room temperature and is soluble in organic solvents. Its mechanism of action involves interaction with estrogen receptors and other molecular targets, contributing to its diverse biological effects. Due to its potential therapeutic applications, 2-Methoxyestradiol has garnered interest in research, particularly in oncology and cardiovascular medicine. However, further studies are needed to fully understand its efficacy and safety in clinical settings.
Formula:C19H26O3
InChI:InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
InChI key:InChIKey=CQOQDQWUFQDJMK-SSTWWWIQSA-N
SMILES:OC=1C=C2C(=CC1OC)C3CCC4(C)C(O)CCC4C3CC2
- Synonyms:
- (17Beta)-2-Methoxyestra-1(10),2,4-Triene-3,17-Diol
- (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol
- (17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol
- (9Xi,14Xi,17Beta)-2-Methoxyestra-1(10),2,4-Triene-3,17-Diol
- 2-Hydroxyestradiol 2-methyl ether
- 2-Hydroxyestradol 2-methyl ether
- 2-Methoxy-E2
- 2-Methoxyestra-1(10),2,4-Triene-3,17-Diol
- 2-Methoxyestra-1,3,5(10)-triene-3,17beta-diol
- 2-Methoxyestra-1,3,5(10)-triene-3,17β-diol
- See more synonyms
- 2-Methoxyestradiol-17beta
- 2Me2
- Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-
- Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17β)-
- Estra-1,3,5(10)-triene-3,17beta-diol, 2-methoxy-
- Estra-1,3,5(10)-triene-3,17β-diol, 2-methoxy-
- Estradiol, 2-methoxy-
- Nsc 659853
- Panzem
- Unii-6I2Qw73Sr5
- 2-Methoxyestradiol