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CAS 362-43-6

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2′,3′-O-Isopropylideneuridine

Description:
2′,3′-O-Isopropylideneuridine is a nucleoside derivative of uridine, characterized by the presence of an isopropylidene group at the 2′ and 3′ positions of the ribose sugar. This modification enhances the stability of the molecule, making it less susceptible to hydrolysis compared to unprotected nucleosides. The compound is typically a white to off-white crystalline solid and is soluble in polar solvents such as water and methanol. It plays a significant role in biochemical research, particularly in the synthesis of nucleoside analogs and in studies related to RNA structure and function. The isopropylidene protection allows for selective reactions at other functional groups, facilitating further chemical modifications. Additionally, 2′,3′-O-Isopropylideneuridine can be utilized in the development of antiviral agents and in the study of nucleic acid interactions. Its CAS number, 362-43-6, is a unique identifier that aids in the cataloging and referencing of this specific chemical substance in scientific literature and databases.
Formula:C12H16N2O6
InChI:InChI=1S/C12H16N2O6/c1-12(2)19-8-6(5-15)18-10(9(8)20-12)14-4-3-7(16)13-11(14)17/h3-4,6,8-10,15H,5H2,1-2H3,(H,13,16,17)/t6-,8-,9-,10-/m1/s1
InChI key:InChIKey=GFDUSNQQMOENLR-PEBGCTIMSA-N
SMILES:C(O)[C@@H]1[C@@]2([C@]([C@@H](O1)N3C(=O)NC(=O)C=C3)(OC(C)(C)O2)[H])[H]
Synonyms:
  • 1-[2,3-O-(1-methylethylidene)pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
  • 2',3'-O-(1-methylethylidene)uridine
  • 2,3-Isopropylideneuridine
  • 2,3-O-Isopropylideneuridine
  • 2′,3′-O-(1-Methylethylidene)uridine
  • Furo[3,4-d]-1,3-dioxole, uridine deriv.
  • NSC 520038
  • Uridine 2′,3′-acetonide
  • Uridine, 2′,3′-O-(1-methylethylidene)-
  • Uridine, 2′,3′-O-isopropylidene-
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