CAS 362-66-3

Stearoyl-CoA

Description:

Stearoyl-CoA, with the CAS number 362-66-3, is a long-chain fatty acyl-CoA derivative, specifically the CoA thioester of stearic acid. It is characterized by its role as an important intermediate in lipid metabolism, particularly in the synthesis and degradation of fatty acids. Stearoyl-CoA is a key substrate for various enzymatic reactions, including fatty acid elongation and desaturation processes. It is involved in the biosynthesis of complex lipids, such as triglycerides and phospholipids, and plays a crucial role in cellular energy storage and membrane structure. The molecule features a long hydrophobic hydrocarbon chain, which contributes to its amphipathic nature, allowing it to interact with both lipid and aqueous environments. Additionally, the presence of the CoA moiety facilitates its participation in metabolic pathways, enabling the transfer of acyl groups to other molecules. Stearoyl-CoA is also significant in signaling pathways and can influence gene expression related to lipid metabolism. Overall, it is a vital component in the biochemistry of living organisms, particularly in energy metabolism and cellular function.

Formula: C₃₉H₇₀N₇O₁₇P₃S

InChI: InChI=1S/C39H70N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(48)67-23-22-41-29(47)20-21-42-37(51)34(50)39(2,3)25-60-66(57,58)63-65(55,56)59-24-28-33(62-64(52,53)54)32(49)38(61-28)46-27-45-31-35(40)43-26-44-36(31)46/h26-28,32-34,38,49-50H,4-25H2,1-3H3,(H,41,47)(H,42,51)(H,55,56)(H,57,58)(H2,40,43,44)(H2,52,53,54)/t28-,32-,33-,34+,38-/m1/s1

InChI key: InChIKey=SIARJEKBADXQJG-LFZQUHGESA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(CCCCCCCCCCCCCCCCC)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Synonyms:

• Coenzyme A, S-octadecanoate
• Coenzyme A, S-stearate
• Octadecanoyl-CoA
• Octadecanoyl-coenzyme A
• S-{(9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} octadecanethioate (non-preferred name)
• S-{1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} octadecanethioate (non-preferred name)
• S-{1-[5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} octadecanethioate (non-preferred name)
• Stearoyl coenzyme A ester
• Stearoyl-CoA
• Stearoyl-coenzyme A
• Stearyl coenzyme A
• Stearyl-CoA

Octadecanoyl Coenzyme A K salt

CAS: 362-66-3

Formula: C39H70N7O17P3S

Purity: >95%

Color and Shape: Solid

Molecular weight: 1034

Ref: 48-19-1800

Stearoyl Coenzyme A, Free acid

CAS: 362-66-3

Purity: 95%

Molecular weight: 1033.376

Ref: 10-C300063

Stearoyl coenzyme A free acid hydrate

CAS: 362-66-3

Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).

Formula: C₃₉H₇₀N₇O₁₇P₃S•H₂O

Purity: Min. 92 Area-%

Color and Shape: White Powder

Molecular weight: 1,052.01 g/mol

Ref: 3D-NS47205