CAS 36239-09-5

Ethyl 3-chloro-3-oxopropanoate

Description:

Ethyl 3-chloro-3-oxopropanoate, with the CAS number 36239-09-5, is an organic compound characterized by its ester functional group and a chloro substituent. It typically appears as a colorless to pale yellow liquid with a fruity odor. This compound features a three-carbon chain with a keto group (carbonyl) and an ethyl ester, making it a versatile intermediate in organic synthesis. Ethyl 3-chloro-3-oxopropanoate is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the chloro group, which can be replaced by various nucleophiles. It is often used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The compound is soluble in organic solvents, and its stability can be influenced by factors such as temperature and the presence of moisture. Safety precautions should be taken when handling this substance, as it may pose health risks if inhaled or ingested, and appropriate protective equipment should be used.

Formula: C₅H₇ClO₃

InChI: InChI=1S/C5H7ClO3/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3

InChI key: InChIKey=KWFADUNOPOSMIJ-UHFFFAOYSA-N

SMILES: C(C(OCC)=O)C(Cl)=O

Synonyms:

• (Chlorocarbonyl)acetic acid ethyl ester
• (Chloroformyl)Acetic Acid Ethyl Ester
• (Ethoxycarbonyl)acetyl chloride
• 2-(Ethoxycarbonyl)acetyl chloride
• 3-Chloro-3-Oxo-Propanoicaciethylester
• 3-Chloro-3-oxopropanoic acid ethyl ester
• 3-Ethoxy-3-oxopropanoyl chloride
• Acetic acid, (chloroformyl)-, ethyl ester
• Aurora Ka-3051
• Carbethoxyacetyl chloride
• Carbethoxyethanoyl chloride
• Carboethoxyacetyl chloride
• Ethanyl Malonyl Chloride
• Ethoxymalonyl chloride
• Ethyl (chlorocarbonyl)acetate
• Ethyl 2-(Chlorocarbonyl)Acetate
• Ethyl 3-Chloro-3-Oxopropionate
• Ethyl 3-chloro-3-oxopropanoate
• Ethyl 3-oxo-3-chloropropanoate
• Ethyl malonoyl chloride
• Ethyl malonyl monochloride
• Ethyl(chloroformyl)acetate
• Ethylpropanedioyl Dichloride
• Malonic acid chloride ethyl ester
• Malonic acid chloride monoethyl ester
• Malonic acid ethyl ester chloride
• Malonic acid monoethyl ester chloride
• Malonic chloride ethyl ester
• Malonic ethyl ester chloride
• Monoethyl malonyl chloride

Ethyl Malonyl Chloride

CAS: 36239-09-5

Formula: C₅H₇ClO₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Yellow to Green clear liquid

Molecular weight: 150.56

Ref: 3B-E0484

Ethyl malonyl chloride, 95%

CAS: 36239-09-5

Ethyl malonyl chloride is used in the syntheses of methanofullerodendimers and 3-pyrrolin-2-ones. It plays a vital role in the preparation of 3,5-disubstituted 1,2,4-oxadiazole derivatives, which are potential peptidomimetic building blocks. It is a versatile acylating agent for propargyl alcohols,

Formula: C₅H₇ClO₃

Purity: 95%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 150.56

Ref: 02-A15616

ethyl 3-chloro-3-oxopropanoate

CAS: 36239-09-5

Formula: C₅H₇ClO₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 150.5603

Ref: IN-DA003Q7F

Ethyl malonyl chloride

CAS: 36239-09-5

Ethyl malonyl chloride

Formula: C₅H₇ClO₃

Purity: 95%

Color and Shape: clear. almost colourless liquid

Molecular weight: 150.56028g/mol

Ref: 54-OR5235

Ethyl Malonyl chloride

CAS: 36239-09-5

Formula: C₅H₇ClO₃

Purity: 95.0%

Color and Shape: Liquid, Clear

Molecular weight: 150.56

Ref: 10-F069285

Ethyl Malonyl Chloride

Controlled Product

CAS: 36239-09-5

Stability Moisture Sensitive
Applications Ethyl Malonyl Chloride is used as a reagent in the synthesis of novel thiadiazoloacrylamide analogs as inhibitors of dengue-2 virus NS2B/NS3 protease. Ethyl Malonyl Chloride is also used as a reagent in the synthesis of quinolone-benzylpiperidine derivatives as acetylcholinesterase inhibitors and antioxidant hybrids for Alzheimer disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liu, H., et al.: Bioorg. Med. Chem., 22, 6344 (2014); Pudlo, M., et al.: Bioorg. Med. Chem., 22, 2496 (2014)

Formula: C₅H₇ClO₃

Color and Shape: Neat

Molecular weight: 150.56

Ref: TR-E922050

Ethyl malonyl chloride

CAS: 36239-09-5

Ethyl malonyl chloride is a compound that belongs to the class of acylating agents. It reacts with the carbonyl group of an organic acid, such as malonic acid, to form an ester. This reaction is catalyzed by a nucleophile such as water or alcohols. Ethyl malonyl chloride has been shown to have anticancer activity and can inhibit protein synthesis in muscle cells by blocking receptor activity and growth factor signaling pathways.

Formula: C₅H₇ClO₃

Purity: 90%Min

Molecular weight: 150.56 g/mol

Ref: 3D-FE36422