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CAS 3624-46-2

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Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:4)

Description:
Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:4), commonly referred to as TTP, is a nucleotide triphosphate that plays a crucial role in cellular metabolism and DNA synthesis. It is a derivative of thymidine, which is one of the four nucleosides that make up DNA. The compound features a ribose sugar, a thymine base, and three phosphate groups, which are responsible for its high-energy properties. The sodium salt form indicates that sodium ions are associated with the triphosphate, enhancing its solubility in aqueous solutions. TTP is essential for DNA polymerase activity during DNA replication and repair processes. Its structure allows it to participate in the formation of phosphodiester bonds, linking nucleotides together to form the DNA backbone. Additionally, TTP is utilized in various biochemical assays and research applications, including polymerase chain reaction (PCR) and other nucleic acid amplification techniques. As a biochemical reagent, it is important to handle TTP with care, as it can be sensitive to hydrolysis and degradation under certain conditions.
Formula:C10H17N2O14P3·4Na
InChI:InChI=1S/C10H17N2O14P3.4Na/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;;;;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;;;/t6-,7+,8+;;;;/m0..../s1
InChI key:InChIKey=QOJFCDIMBHCWCP-ZKRIHRHSSA-N
SMILES:O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C2)C=C(C)C(=O)N1.[Na]
Synonyms:
  • 2-Deoxythymidine 5-triphosphoric acid trisodium salt (dTTP)
  • TTP tetrasodium salt
  • Thymidine 5'-Triphosphate Sodium Salt
  • Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:4)
  • Thymidine 5′-(tetrahydrogen triphosphate), tetrasodium salt
  • Thymidine 5′-triphosphate, tetrasodium salt
  • Thymidine 5-triphosphate tetrasodium salt
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