CAS 36268-67-4

4-(Methanesulfonylamino)benzonitrile

Description:

4-(Methanesulfonylamino)benzonitrile, with the CAS number 36268-67-4, is an organic compound characterized by the presence of a benzonitrile moiety substituted with a methanesulfonylamino group. This compound typically appears as a solid at room temperature and is soluble in polar organic solvents. The methanesulfonylamino group contributes to its potential as a versatile building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of the nitrile functional group indicates that it may exhibit reactivity typical of nitriles, such as nucleophilic addition. Additionally, the sulfonamide functionality can influence the compound's biological activity and solubility properties. Its structural features suggest potential applications in medicinal chemistry, where it may serve as a lead compound for further modifications aimed at enhancing efficacy or reducing toxicity. As with many chemical substances, handling should be conducted with care, adhering to safety protocols to mitigate any risks associated with its use.

Formula: C₈H₈N₂O₂S

InChI: InChI=1/C8H8N2O2S/c1-13(11,12)10-8-4-2-7(6-9)3-5-8/h2-5,10H,1H3

SMILES: CS(=O)(=O)Nc1ccc(cc1)C#N

Synonyms:

• N-(4-cyanophenyl)methanesulfonamide

4-(METHANESULFONYLAMINO)BENZONITRILE

CAS: 36268-67-4

Formula: C₈H₈N₂O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 196.2263

Ref: IN-DA003K8T

4-(Methanesulfonylamino)benzonitrile

CAS: 36268-67-4

4-(Methanesulfonylamino)benzonitrile

Purity: ≥95%

Molecular weight: 196.23g/mol

Ref: 54-OR470012

N-(4-cyanophenyl)methanesulfonamide

CAS: 36268-67-4

Formula: C₈H₈N₂O₂S

Purity: >97%

Color and Shape: Solid

Molecular weight: 196.22

Ref: 10-F351581

4-(Methanesulfonylamino)benzonitrile

CAS: 36268-67-4

4-(Methanesulfonylamino)benzonitrile is a potent and selective vanilloid receptor antagonist. It has been shown to inhibit the uptake of nitro compounds by rat brain synaptosomes in vitro and to block the binding of [3H]nitro-N-methyl-4-phenylpyridinium ion (NMPA) to rat brain membranes. 4-(Methanesulfonylamino)benzonitrile has been shown to bind to albumin, which may be an important factor in its pharmacokinetics. This drug also binds with serum albumin, which may reduce its absorption after oral administration.

Formula: C₈H₈N₂O₂S

Purity: Min. 95%

Molecular weight: 196.23 g/mol

Ref: 3D-LBA26867